SCHEMBL1496975

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496946	0.88	KDM4E (0.41)	ALDH1A1KDM4EHPGDHSD17B10MEN1
	SCHEMBL1497093	0.86	ALDH1A1 (0.44)	ALDH1A1KDM4EHPGDHSD17B10MEN1
	SCHEMBL1497015	0.85	ALDH1A1 (0.36)	ALDH1A1KDM4EHPGDHSD17B10MEN1
	SCHEMBL11918275	0.83	ALDH1A1 (0.34)	ALDH1A1KDM4EHPGDHSD17B10MEN1
	SCHEMBL1497010	0.81	HIF1A (0.39)	LMNAHIF1APOLBHRH3HDAC1
	SCHEMBL1496927	0.81	RAB9A (0.37)	ALDH1A1KDM4EHPGDHSD17B10MEN1
	SCHEMBL7999005	0.80	HDAC3 (0.39)	ALDH1A1KDM4ELMNAHIF1AGAA
	SCHEMBL1497140	0.80	HDAC1 (0.41)	USP2LMNAHIF1AHDAC1MCHR1
	SCHEMBL1483172	0.80	HIF1A (0.42)	MEN1KMT2AHIF1AHDAC1HDAC2
	SCHEMBL1496978	0.79	RAB9A (0.39)	ALDH1A1KDM4EHPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.