SCHEMBL1496946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496975	0.88	ALDH1A1 (0.41)	KDM4EALDH1A1MEN1KMT2AHSD17B10
	SCHEMBL1496908	0.87	ALDH1A1 (0.41)	KDM4EALDH1A1MEN1KMT2AHSD17B10
	SCHEMBL1496937	0.86	ALDH1A1 (0.37)	KDM4EALDH1A1MEN1KMT2AHSD17B10
	SCHEMBL13374699	0.84	ALDH1A1 (0.35)	KDM4EALDH1A1MEN1KMT2AHSD17B10
	SCHEMBL1496917	0.83	SIGMAR1 (0.40)	POLBLMNAMCHR2MCHR1NAMPT
	SCHEMBL1497012	0.82	SIGMAR1 (0.42)	USP2NAMPT
	SCHEMBL1497006	0.82	MAPT (0.37)	KDM4EALDH1A1MEN1KMT2AHSD17B10
	SCHEMBL1496862	0.81	HTR5A (0.40)	MEN1KMT2ANAMPTHTR5A
	SCHEMBL1496919	0.81	SIGMAR1 (0.41)	KDM4EALDH1A1POLBNAMPT
	SCHEMBL10476400	0.81	KDM4E (0.37)	KDM4EALDH1A1KMT2AHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.