Niacin

Niacin

SCHEMBL1498010

O=C([O-])c1cccnc1.O=C([O-])c1cccnc1.[Fe+2]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
GAA P10253 2/20 0.63
APP P05067 1/20 0.63
HCAR3 P49019 1/20 0.63
HCAR2 Q8TDS4 1/20 0.63
F7 P08709 1/20 0.61
F3 P13726 1/20 0.61
SARM1 Q6SZW1 1/20 0.61
SIRT2 Q8IXJ6 1/20 0.61
SIRT6 Q8N6T7 1/20 0.61
SIRT1 Q96EB6 1/20 0.61
SIRT3 Q9NTG7 1/20 0.61
SIRT5 Q9NXA8 1/20 0.61
SIRT4 Q9Y6E7 1/20 0.61
HDAC1 Q13547 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
PLOD2 O00469 2/20 0.53
LMNA P02545 3/20 0.52
THRB P10828 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niacin SCHEMBL18304342 0.98 ALDH1A1 (0.61) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL587526 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL3498987 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL6012008 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL23780930 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL25269786 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL10357700 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL1943861 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL308681 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2
Niacin SCHEMBL987479 0.96 ALDH1A1 (0.63) ALDH1A1GAAAPPHCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117337138-A Controlled release delivery compositions for extending shelf life of perishable goods and methods of making and using the same RYP实验室有限公司 2024-01-02 CN claimed
EP-3307091-B1 FOOD COMPOSTION COMPRISING IRON NICOTINATE COMPLEX AND PHENOLIC CHROMOPHORE COMPOUNDS NESTLE SA (CH) 2020-10-14 EP claimed
EP-3307091-A1 IRON NICOTINATE COMPOSITION Nestec S.A. (CH) 2018-04-18 EP claimed
US-20180092393-A1 IRON NICOTINATE COMPOSITION Société des Produits Nestlé S.A. (CH) 2018-04-05 US claimed
WO-2016198285-A1 IRON NICOTINATE COMPOSITION NESTEC S.A. (CH) 2016-12-15 WO claimed
CN-117337138-A Controlled release delivery compositions for extending shelf life of perishable goods and methods of making and using the same RYP实验室有限公司 2024-01-02 CN disclosed
US-20230145406-A1 DIVALENT METAL-CONTAINING BIOMATERIALS AND METHODS OF USE UNIVERSITY OF OREGON (US) 2023-05-11 US disclosed
EP-3307091-B1 FOOD COMPOSTION COMPRISING IRON NICOTINATE COMPLEX AND PHENOLIC CHROMOPHORE COMPOUNDS NESTLE SA (CH) 2020-10-14 EP disclosed
EP-3307091-B1 FOOD COMPOSTION COMPRISING IRON NICOTINATE COMPLEX AND PHENOLIC CHROMOPHORE COMPOUNDS NESTLE SA (CH) 2020-10-14 EP disclosed
US-10738068-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates Centre National de la Recherche Scientifique—CNRS (FR) 2020-08-11 US disclosed
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-12-06 US disclosed
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2018-09-04 US disclosed
WO-2016198285-A1 IRON NICOTINATE COMPOSITION NESTEC S.A. (CH) 2016-12-15 WO disclosed
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST Centre National De La Recherche Scientifique - CNR S (FR) 2011-03-03 US disclosed
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS- (FR) 2010-09-09 US disclosed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 US disclosed
EP-2015647-A2 IRON COMPLEX FOR USE IN THE TREATMENT AND/OR PREVENTION OF NUTRITIONAL DISORDERS UNILEVER N.V. (NL) 2009-01-21 EP disclosed
CN-101043824-A Iron complex for curing and / or preventing malnutrition UNILEVER NV (NL) 2007-09-26 CN disclosed
WO-2006037449-A2 IRON COMPLEX FOR USE IN THE TREATMENT AND/OR PREVENTION OF NUTRITIONAL DISORDERS UNILEVER N.V. (NL) 2006-04-13 WO disclosed
US-20060078594-A1 Iron complex CONOPCO, INC., D/B/A UNILEVER 2006-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060078594-A1 Iron complex SLC40A1, FECH, TFRC ALDH1A1 3385/4885GAA 415/4885APP 3646/4885
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST MITF, SLCO2B1, SLCO2A1 ALDH1A1 2972/4885GAA 101/4885APP 3123/4885
US-20180092393-A1 IRON NICOTINATE COMPOSITION NAMPT, NAPRT, NNT ALDH1A1 1824/4885GAA 1693/4885APP 1537/4885
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE SLCO2A1, SLCO4C1, SLCO2B1 ALDH1A1 150/4885GAA 168/4885APP 4634/4885
US-10065979-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates SLC39A3, SLC40A1, AOC3 ALDH1A1 488/4885GAA 780/4885APP 3914/4885
US-20180346500-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 ALDH1A1 502/4885GAA 796/4885APP 3948/4885
US-10738068-B2 Organic/inorganic hybrid nanoparticulates made from iron carboxylates SLC40A1, FECH, FTH1 ALDH1A1 301/4885GAA 447/4885APP 4023/4885
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 ALDH1A1 488/4885GAA 780/4885APP 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.