Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14980671 | 0.89 | USP2 (0.37) | MEN1ALDH1A1KMT2AHSD17B10USP2 | |
| SCHEMBL14980658 | 0.80 | CYP1A2 (0.38) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL14980668 | 0.75 | USP2 (0.38) | PLK1USP2 | |
| SCHEMBL14980641 | 0.65 | MEN1 (0.31) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14981115 | 0.65 | NTRK1 (0.33) | — | |
| SCHEMBL26296832 | 0.63 | CYP1A2 (0.43) | MEN1ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL16366864 | 0.63 | CYP1A2 (0.31) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL14981227 | 0.62 | POLB (0.32) | POLB | |
| SCHEMBL14980659 | 0.62 | ACHE (0.32) | MEN1ALDH1A1 | |
| SCHEMBL13174918 | 0.57 | ALDH1A1 (0.38) | PLK1MEN1ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |