SCHEMBL1500586

SCHEMBL1500586

CCCCCCCCCCCCCC([CH]C(CC)C(C)(C)C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
DNM1 Q05193 2/20 0.34
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
CA2 P00918 1/20 0.34
OPRM1 P35372 1/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
FDPS P14324 4/20 0.32
GPR84 Q9NQS5 3/20 0.32
SPHK1 Q9NYA1 1/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11071882 0.78 LMNA (0.43) LMNADNM1ADH1BADH1CADH1A
SCHEMBL27744726 0.78 LMNA (0.43) LMNADNM1ADH1BADH1CADH1A
SCHEMBL29035274 0.68 OPRM1 (0.39) LMNADNM1ADH1BADH1CADH1A
SCHEMBL1082919 0.67 TSHR (0.44) LMNADNM1CA2OPRM1TSHR
SCHEMBL27947143 0.67 FDPS (0.48) LMNADNM1CA2OPRM1TSHR
SCHEMBL19123662 0.67 FDPS (0.48) LMNADNM1CA2OPRM1TSHR
SCHEMBL5680379 0.67 FDPS (0.48) LMNADNM1CA2OPRM1TSHR
SCHEMBL19565241 0.67 FDPS (0.43) LMNADNM1CA2OPRM1TSHR
SCHEMBL29344416 0.67 FDPS (0.48) LMNADNM1CA2OPRM1TSHR
SCHEMBL28846487 0.66 TSHR (0.50) LMNADNM1OPRM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997009376-A1 STABILIZATION SYSTEMS FOR POLYMERIC MATERIALS IN PELLET FORM CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 1997-03-13 WO claimed
US-9745425-B2 Cycloaliphatic polyphosphite DOVER CHEMICAL CORPORATION (US) 2017-08-29 US disclosed
US-20140378590-A1 CYCLOALIPHATIC POLYPHOSPHITE DOVER CHEMICAL CORPORATION (US) 2014-12-25 US disclosed
US-8450412-B2 Flame retardant polyamide composition, method, and article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-28 US disclosed
US-8193260-B2 Liquid phase; reacting p-cresol with styrene in presenc eof acid catalyst CHEMTURA CORPORATION (US) 2012-06-05 US disclosed
US-20110152431-A1 FLAME RETARDANT POLYAMIDE COMPOSITION, METHOD, AND ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110152420-A1 POLY(ARYLENE ETHER)/POLYAMIDE COMPOSITIONS, METHODS, AND ARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-06-23 US disclosed
US-20110086314-A1 MELTS ROHM AND HAAS ELECTRONIC MATERIAL LLC (US) 2011-04-14 US disclosed
US-7902280-B2 Liquid styrenated phenolic compositions and processes for forming same CHEMTURA CORPORATION (US) 2011-03-08 US disclosed
US-20090214980-A1 Melts ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2009-08-27 US disclosed
US-20090005478-A1 LIQUID STYRENATED PHENOLIC COMPOSITIONS AND PROCESSES FOR FORMING SAME SI GROUP, INC. 2009-01-01 US disclosed
US-20080207804-A1 Stabilization of polymers with styrenated-p-cresols ADDIVANT USA, LLC 2008-08-28 US disclosed
US-6534557-B2 Radiation-curable, optical fiber primary coating system DSM N.V. (NL) 2003-03-18 US disclosed
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US disclosed
US-6184411-B1 REMOVAL OF RESIDUAL TIN CATALYST FROM SUBSTITUTED HIGHER ALIPHATIC ESTERS OF HYDROXYHYDROCINNAMIC ACIDS MADE BY THE TIN SOURCE-CATALYZED TRANSESTERIFICATION REACTION BETWEEN THE CORRESPONDING LOWER ALKYL ESTER AND HIGHER ALKANOL CIBA SPECIALTY CHEMICALS CORPORATION 2001-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207804-A1 Stabilization of polymers with styrenated-p-cresols GRHPR, REN, STK39 LMNA 1063/4885DNM1 4665/4885ADH1B 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.