Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762101 | 0.77 | CYP2C9 (0.41) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL9761111 | 0.74 | CYP2C9 (0.38) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL15055948 | 0.71 | ALDH1A1 (0.47) | CYP2C19 | |
| SCHEMBL20692743 | 0.68 | CYP2C9 (0.41) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL15055757 | 0.68 | — | — | |
| SCHEMBL2301820 | 0.67 | — | — | |
| SCHEMBL15055678 | 0.65 | MGLL (0.37) | TSHRTDP1 | |
| SCHEMBL5956451 | 0.65 | — | — | |
| SCHEMBL2303762 | 0.64 | — | — | |
| SCHEMBL18390907 | 0.64 | KDM4E (0.48) | CYP2C9TSHRCYP2C19MTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473584-B | Thiophene-or furan-substituted isothiazoline compounds | 勃林格殷格翰动物保健美国公司 | 2020-01-31 | — | — | CN | disclosed |
| US-10407383-B2 | Cyclopentene and cyclopentadiene compounds for controlling invertebrate pests | BASF SE (DE) | 2019-09-10 | — | — | US | disclosed |
| EP-3102563-B1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-3013822-B1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | MERIAL INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9732051-B2 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| EP-3102563-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-20160355466-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-12-08 | — | — | US | disclosed |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | MERIAL, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| EP-3013822-A1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | Merial, Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| EP-3013820-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015114157-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |
| WO-2014206910-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014206909-A1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2014-12-11 | — | — | US | disclosed |
| EP-2794601-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092943-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BROX, TUBA3C, SYMPK | CYP2C9 83/4885TSHR 3743/4885CYP2C19 341/4885 |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | PTMS, DDT, PIR | CYP2C9 48/4885TSHR 814/4885CYP2C19 242/4885 |
| US-10407383-B2 | Cyclopentene and cyclopentadiene compounds for controlling invertebrate pests | PPIE, ECI1, PPID | CYP2C9 298/4885TSHR 4726/4885CYP2C19 645/4885 |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | PIR, ACHE, INMT | CYP2C9 336/4885TSHR 2195/4885CYP2C19 1104/4885 |
| US-20160355466-A1 | CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | PPIE, ECI1, PPID | CYP2C9 298/4885TSHR 4726/4885CYP2C19 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.