Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465624 | 0.90 | TSHR (0.37) | HPSEEPHX2CASP2HDAC3HDAC4 | |
| SCHEMBL23120734 | 0.90 | IDUA (0.39) | PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15194559 | 0.88 | IDUA (0.36) | PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14124440 | 0.87 | TSHR (0.48) | HPSEEPHX2CASP2PRMT1SMN1; SMN2 | |
| SCHEMBL15058341 | 0.86 | SLC6A5 (0.51) | HPSECASP2FAAHNAAASMN1; SMN2 | |
| SCHEMBL17881973 | 0.86 | CASP2 (0.42) | HPSEEPHX2CASP2HDAC3HDAC4 | |
| SCHEMBL17747044 | 0.85 | EPHX2 (0.48) | EPHX2FAAHPRMT1 | |
| SCHEMBL29552353 | 0.85 | PRMT1 (0.43) | HPSEEPHX2CASP2PRMT1NAAA | |
| SCHEMBL17122488 | 0.84 | CASP2 (0.56) | EPHX2CASP2FAAHNAAADNM1 | |
| SCHEMBL23280904 | 0.83 | GAA (0.51) | HPSEEPHX2CASP2FAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793947-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2021-02-03 | — | — | EP | disclosed |
| US-10675359-B2 | Enzymatic conjugation of antibodies | INNATE PHARMA (FR) | 2020-06-09 | — | — | US | disclosed |
| EP-3564259-A2 | RECOGNITION TAGS FOR TGASE-MEDIATED CONJUGATION | Innate Pharma (FR) | 2019-11-06 | — | — | EP | disclosed |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2019-10-08 | — | — | US | disclosed |
| US-20190169601-A1 | RECOGNITION TAGS FOR TGASE-MEDIATED CONJUGATION | INNATE PHARMA (FR) | 2019-06-06 | — | — | US | disclosed |
| EP-2872894-B1 | SCREENING OF CONJUGATED ANTIBODIES | INNATE PHARMA (FR) | 2019-04-17 | — | — | EP | disclosed |
| EP-3240573-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2019-03-20 | — | — | EP | disclosed |
| US-10132799-B2 | Screening of conjugated antibodies | INNATE PHARMA (FR) | 2018-11-20 | — | — | US | disclosed |
| EP-2793949-B1 | ENZYMATIC CONJUGATION OF ANTIBODIES | INNATE PHARMA (FR) | 2018-08-22 | — | — | EP | disclosed |
| US-10036010-B2 | Recognition tags for TGase-mediated conjugation | INNATE PHARMA (FR) | 2018-07-31 | — | — | US | disclosed |
| EP-2872894-A2 | SCREENING OF CONJUGATED ANTIBODIES | Innate Pharma (FR) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014202775-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2014-12-24 | — | — | WO | disclosed |
| US-20140356385-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | ARARIS BIOTECH LTD (CH) | 2014-12-04 | — | — | US | disclosed |
| EP-2793947-A2 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | Innate Pharma (FR) | 2014-10-29 | — | — | EP | disclosed |
| EP-2793949-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | Innate Pharma (FR) | 2014-10-29 | — | — | EP | disclosed |
| WO-2014072482-A1 | RECOGNITION TAGS FOR TGASE-MEDIATED CONJUGATION | INNATE PHARMA (FR) | 2014-05-15 | — | — | WO | disclosed |
| WO-2014009426-A2 | SCREENING OF CONJUGATED ANTIBODIES | INNATE PHARMA (FR) | 2014-01-16 | — | — | WO | disclosed |
| US-20130189287-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | PAUL SCHERRER INSTITUT | 2013-07-25 | — | — | US | disclosed |
| WO-2013092998-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | INNATE PHARMA (FR) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092983-A2 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10675359-B2 | Enzymatic conjugation of antibodies | DNPEP, MPO, FCGR3B | HPSE 110/4885EPHX2 618/4885CASP2 3623/4885 |
| US-20130189287-A1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | DNPEP, ENPEP, PEPD | HPSE 114/4885EPHX2 937/4885CASP2 3621/4885 |
| US-10434180-B2 | Enzymatic conjugation of polypeptides | DNPEP, ENPEP, PEPD | HPSE 132/4885EPHX2 876/4885CASP2 3625/4885 |
| US-10132799-B2 | Screening of conjugated antibodies | FCGR2A, TGM2, TGM6 | HPSE 1506/4885EPHX2 2290/4885CASP2 4535/4885 |
| US-10036010-B2 | Recognition tags for TGase-mediated conjugation | TGM2, TGM3, TGM6 | HPSE 316/4885EPHX2 952/4885CASP2 4494/4885 |
| US-20140356385-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | DNPEP, MPO, FCGR3B | HPSE 110/4885EPHX2 618/4885CASP2 3623/4885 |
| US-20190169601-A1 | RECOGNITION TAGS FOR TGASE-MEDIATED CONJUGATION | TGM2, TGM3, TGM6 | HPSE 316/4885EPHX2 952/4885CASP2 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.