Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | HINT1 | P49773 | 3/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 4/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496063 | 0.93 | TGM2 (0.54) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL237754 | 0.86 | HINT1 (0.58) | NT5ETGM2HINT1KRASSTING1 | |
| SCHEMBL18841403 | 0.79 | NT5E (0.64) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL1120568 | 0.79 | HINT1 (0.59) | NT5ETGM2HINT1KRASSTING1 | |
| Phosphoric Acid SCHEMBL25402859 | 0.79 | NT5E (0.63) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL16555277 | 0.79 | HINT1 (0.55) | NT5ETGM2HINT1KRASSTING1 | |
| Phosphoric Acid SCHEMBL1299515 | 0.79 | NT5E (0.63) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL1299520 | 0.79 | NT5E (0.58) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL1299533 | 0.79 | NT5E (0.58) | NT5ETGM2HINT1IMPDH2IMPDH1 | |
| SCHEMBL19183426 | 0.78 | NT5E (0.57) | NT5ETGM2HINT1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297175-A2 | MRNA CAP ANALOGS | Uniwersytet Warszawski (PL) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009149253-A2 | MRNA CAP ANALOGS | UNIWERSYTET WARSZAWSKI (PL) | 2009-12-10 | — | — | WO | disclosed |
| EP-1575974-B1 | MODIFIED GUANOSINES HAVING FLAVOURING ACTIVITY | FRUCTAMINE SPA (IT) | 2008-03-19 | — | — | EP | disclosed |
| US-20050288499-A1 | Modified guanosines having flavouring activity | KERRY GROUP SERVICES INTERNATIONAL LIMITED (IE) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288499-A1 | Modified guanosines having flavouring activity | GMPS, RNMT, CGAS | NT5E 439/4885TGM2 361/4885HINT1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.