SCHEMBL16496063

SCHEMBL16496063

COC(C)(OP(=O)(O)OP(=O)(O)O)[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.54
▸ NT5E P21589 1/20 0.53
▸ FUT5 Q11128 1/20 0.51
▸ KRAS P01116 5/20 0.49
▸ HINT1 P49773 3/20 0.49
▸ IMPDH2 P12268 1/20 0.49
▸ IMPDH1 P20839 1/20 0.49
▸ POLB P06746 1/20 0.47
▸ STING1 Q86WV6 2/20 0.47
▸ PDE3B Q13370 1/20 0.47
▸ PDE3A Q14432 1/20 0.47
▸ P2RY2 P41231 1/20 0.47
▸ P2RY4 P51582 1/20 0.47
▸ P2RY6 Q15077 1/20 0.47
▸ DCPS Q96C86 1/20 0.46
▸ GSK3A P49840 1/20 0.45
▸ RPS6KA3 P51812 1/20 0.45
▸ MAPK14 Q16539 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1506529 0.93 NT5E (0.56) TGM2NT5EFUT5KRASHINT1
SCHEMBL237754 0.83 HINT1 (0.58) TGM2NT5EKRASHINT1STING1
Guanosine SCHEMBL9827513 0.80 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL6066347 0.80 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL30589987 0.80 NT5E (0.69) TGM2NT5EFUT5KRASHINT1
SCHEMBL23477431 0.79 NT5E (0.70) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL30125158 0.79 NT5E (0.68) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL19211836 0.79 NT5E (0.68) TGM2NT5EFUT5KRASHINT1
Guanosine SCHEMBL4625995 0.79 NT5E (0.68) TGM2NT5EFUT5KRASHINT1
SCHEMBL309061 0.79 TGM2 (0.55) TGM2NT5EFUT5KRASHINT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9067964-B2 Complex and method for enhancing nuclear delivery OLIGOMER SCIENCES AB (SE) 2015-06-30 — — US disclosed
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY OLIGOMER SCIENCES AB (SE) 2011-12-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110306138-A1 COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY SNRPE, SNRPA, HNRNPH3 TGM2 1855/4885NT5E 390/4885FUT5 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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