Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307930 | 0.82 | TSHR (0.35) | TSHRALDH1A1ALOX15TRPA1 | |
| SCHEMBL28745209 | 0.81 | ALDH1A1 (0.35) | TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL15907701 | 0.79 | TSHR (0.39) | TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL15027382 | 0.78 | TSHR (0.35) | TSHRALDH1A1ALOX15TRPA1 | |
| SCHEMBL17365007 | 0.77 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEP | |
| SCHEMBL765779 | 0.77 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEP | |
| SCHEMBL5016256 | 0.77 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEP | |
| SCHEMBL890533 | 0.77 | — | — | |
| SCHEMBL17464876 | 0.75 | THRB (0.35) | TSHR | |
| SCHEMBL17464872 | 0.75 | LMNA (0.37) | TSHRALDH1A1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741373-A | Adhesives and sealants comprising esters based on 2-propylheptanol | BASF SE | 2012-10-17 | — | — | CN | claimed |
| CN-101959838-A | Method for the production of (meth)acrylates of C10 alcohol mixtures | BASF SE | 2011-01-26 | — | — | CN | claimed |
| CN-100526280-C | Hydroformylation of isobutene-containing butenes | EXXONMOBIL CHEM PATENTS INC (US) | 2009-08-12 | — | — | CN | claimed |
| CN-1856460-A | Hydroformylation of isobutene-containing butenes | EXXONMOBIL CHEM PATENTS INC (US) | 2006-11-01 | — | — | CN | claimed |
| US-9670205-B2 | Toll like receptor modulator compounds | GILEAD SCIENCES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160289229-A1 | TOLL LIKE RECEPTOR MODULATOR COMPOUNDS | GILEAD SCIENCES, INC. | 2016-10-06 | — | — | US | disclosed |
| CN-105683147-A | Method for producing carboxylic acid esters and the use thereof as plasticizers | 巴斯夫欧洲公司 | 2016-06-15 | — | — | CN | disclosed |
| US-20130171385-A1 | REACTING CYCLOPENTADIENE AND MALEIC ANHYDRIDE FOR THE PRODUCTION OF PLASTICIZERS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-07-04 | — | — | US | disclosed |
| CN-102741373-A | Adhesives and sealants comprising esters based on 2-propylheptanol | BASF SE | 2012-10-17 | — | — | CN | disclosed |
| CN-102666455-A | Method for producing decanols by means of hydrogenating decenals | EVONIK OXENO GMBH | 2012-09-12 | — | — | CN | disclosed |
| CN-102596928-A | 2, 5-furandicarboxylic acid ester containing isomeric decanol and application thereof | EVONIK OXENO GMBH | 2012-07-18 | — | — | CN | disclosed |
| CN-101959838-A | Method for the production of (meth)acrylates of C10 alcohol mixtures | BASF SE | 2011-01-26 | — | — | CN | disclosed |
| CN-100526280-C | Hydroformylation of isobutene-containing butenes | EXXONMOBIL CHEM PATENTS INC (US) | 2009-08-12 | — | — | CN | disclosed |
| CN-1856460-A | Hydroformylation of isobutene-containing butenes | EXXONMOBIL CHEM PATENTS INC (US) | 2006-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171385-A1 | REACTING CYCLOPENTADIENE AND MALEIC ANHYDRIDE FOR THE PRODUCTION OF PLASTICIZERS | ADH1A, ADH1C, ADH5 | TSHR 3932/4885ALDH1A1 100/4885MAPK1 2960/4885 |
| US-20160289229-A1 | TOLL LIKE RECEPTOR MODULATOR COMPOUNDS | TLR8, TLR3, TLR6 | TSHR 1106/4885ALDH1A1 3811/4885MAPK1 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.