SCHEMBL15067115

SCHEMBL15067115

C=CCOc1[c]c(F)ccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
PTPRC P08575 1/20 0.33
LIG1 P18858 1/20 0.32
CA12 O43570 5/20 0.32
CA1 P00915 5/20 0.32
CA9 Q16790 5/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3840978 0.86 HPGD (0.38) MAPTL3MBTL1CYP3A4HPGDTSHR
SCHEMBL1990168 0.78 TSHR (0.34) CYP3A4HPGDTSHRMAPK1HSD17B10
SCHEMBL15068118 0.78 ADRA2A (0.36) MAPTCYP3A4HPGDTSHRMAPK1
SCHEMBL17460051 0.77 AGER (0.35) MAPTL3MBTL1CYP3A4HPGDTSHR
SCHEMBL159421 0.75 NQO1 (0.36) MAPTL3MBTL1CYP3A4TSHRTP53
SCHEMBL15067388 0.74 HTR2C (0.39) MAPTL3MBTL1HPGDTSHRMAPK1
SCHEMBL15939882 0.74 MAPT (0.33) MAPTL3MBTL1ADRA2AADRA2BADRA2C
SCHEMBL4535895 0.73 APP (0.30)
SCHEMBL16213529 0.72 MAPT (0.39) MAPTL3MBTL1CYP3A4HPGDTSHR
SCHEMBL21680729 0.72 PTPN1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10941122-B2 Diaminotriazine derivatives as herbicides BASF SE (DE) 2021-03-09 US claimed
EP-3129359-B1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2021-03-03 EP claimed
CN-107033139-B Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide 拜耳知识产权有限责任公司 2019-11-19 CN claimed
US-9975889-B2 Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-05-22 US claimed
US-9914728-B2 Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-03-13 US claimed
CN-107033139-A It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of fungicide 拜耳知识产权有限责任公司 2017-08-11 CN claimed
US-20170044153-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH 2017-02-16 US claimed
US-20170044154-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-16 US claimed
EP-3129359-A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2017-02-15 EP claimed
US-20170022170-A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2017-01-26 US claimed
WO-2015155272-A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2015-10-15 WO claimed
US-11147272-B2 Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients MITSUI CHEMICALS ARGRO, INC. (JP) 2021-10-19 US disclosed
US-10941122-B2 Diaminotriazine derivatives as herbicides BASF SE (DE) 2021-03-09 US disclosed
EP-3129359-B1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES BASF SE (DE) 2021-03-03 EP disclosed
CN-107266382-B Heteroarylpiperidine and piperazine derivatives as fungicides 拜耳知识产权有限责任公司 2020-10-27 CN disclosed
EP-2797899-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES Bayer Intellectual Property GmbH (DE) 2014-11-05 EP disclosed
CN-104011032-A Heteroarylpiperidine and piperazine derivatives as fungicides BAYER IP GMBH 2014-08-27 CN disclosed
US-20140005224-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-01-02 US disclosed
CN-103492379-A Heteroarylpiperidine and piperazine derivatives as fungicides BAYER IP GMBH 2014-01-01 CN disclosed
WO-2013098229-A2 HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044154-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES PRXL2A, CYP1A1, CAT MAPT 3867/4885L3MBTL1 2120/4885CYP3A4 48/4885
US-10941122-B2 Diaminotriazine derivatives as herbicides DDT, CBR3, HDHD5 MAPT 4514/4885L3MBTL1 602/4885CYP3A4 2922/4885
US-20170044153-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES PRXL2A, CYP1A1, CAT MAPT 3867/4885L3MBTL1 2120/4885CYP3A4 48/4885
US-20140005224-A1 HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES PRXL2A, CYP1A1, CAT MAPT 3867/4885L3MBTL1 2120/4885CYP3A4 48/4885
US-20170022170-A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES DDT, CBR3, HDHD5 MAPT 4514/4885L3MBTL1 602/4885CYP3A4 2922/4885
US-11147272-B2 Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients PNPO, PDXK, PLPBP MAPT 2212/4885L3MBTL1 2140/4885CYP3A4 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.