Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752221 | 0.86 | TAAR1 (0.50) | ALOX15TAAR1ALOX12GABRA1GABRB2 | |
| SCHEMBL26026393 | 0.86 | HTR2A (0.47) | ALOX15TAAR1PKMALOX12GABRA1 | |
| SCHEMBL14239569 | 0.85 | ALOX15 (0.63) | ALOX15TAAR1PKMALOX12LDHA | |
| SCHEMBL11156645 | 0.84 | ALOX15 (0.47) | ALOX15PKMALOX12GABRA1GABRB2 | |
| SCHEMBL11950523 | 0.83 | CA2 (0.48) | ALOX15TAAR1PKMHSD17B1 | |
| SCHEMBL12056053 | 0.82 | PPARA (0.59) | ALOX15PKMALOX12LDHAPPARD | |
| SCHEMBL806723 | 0.81 | CA2 (0.63) | ALOX15ALOX12LDHAFOSTTR | |
| SCHEMBL20286678 | 0.81 | CA2 (0.63) | ALOX15TAAR1PKM | |
| SCHEMBL2436464 | 0.80 | ALOX15 (0.49) | ALOX15TAAR1PKMALOX12LDHA | |
| SCHEMBL18264884 | 0.78 | PKM (0.46) | ALOX15TAAR1PKMLDHATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| US-9115145-B2 | Tocotrienol derivatives and associated methods | FIRST TECH INTERNATIONAL LIMITED (CN) | 2015-08-25 | — | — | US | disclosed |
| US-20140329808-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | EL SAYED KHALID A (US) | 2014-11-06 | — | — | US | disclosed |
| US-8816071-B2 | Tocotrienol derivatives and associated methods | FIRST TECH INTERNATIONAL LIMITED (CN) | 2014-08-26 | — | — | US | disclosed |
| US-20130165435-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | ALOX15 1555/4885TAAR1 4871/4885PKM 716/4885 |
| US-20140329808-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | TTPA, TOP2A, GSTO1 | ALOX15 70/4885TAAR1 614/4885PKM 4809/4885 |
| US-20130165435-A1 | TOCOTRIENOL DERIVATIVES AND ASSOCIATED METHODS | TTPA, TOP2A, GSTO1 | ALOX15 70/4885TAAR1 614/4885PKM 4809/4885 |
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | ALOX15 1555/4885TAAR1 4871/4885PKM 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.