SCHEMBL150756

SCHEMBL150756

N=C(N)c1ccc(N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 3/20 1.00
MASP2 O00187 1/20 1.00
THPO P40225 1/20 1.00
PRSS1 P07477 5/20 0.94
PRSS3 P35030 5/20 0.94
F2 P00734 4/20 0.94
APEX1 P27695 1/20 0.94
LMNA P02545 2/20 0.62
F10 P00742 2/20 0.57
F12 P00748 1/20 0.57
F7 P08709 1/20 0.57
F3 P13726 1/20 0.57
PKM P14618 1/20 0.57
ST14 Q9Y5Y6 2/20 0.56
PRMT5 O14744 1/20 0.56
PRMT1 Q99873 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
HSD17B10 Q99714 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL538862 0.97 PRSS1 (1.00) PLAUMASP2THPOPRSS1PRSS3
Ammonia Solution, Strong SCHEMBL28058272 0.97 PLAU (0.94) PLAUMASP2THPOPRSS1PRSS3
Hydrochloric Acid SCHEMBL236095 0.97 PRSS1 (1.00) PLAUMASP2THPOPRSS1PRSS3
Hydrochloric Acid SCHEMBL28256621 0.95 PRSS1 (0.95) PLAUMASP2THPOPRSS1PRSS3
Carbamic Acid SCHEMBL28064780 0.90 PLAU (0.81) PLAUMASP2THPOPRSS1PRSS3
SCHEMBL537030 0.87 LMNA (0.77) PLAUMASP2THPOPRSS1PRSS3
Acetic Acid SCHEMBL7398032 0.86 MASP2 (0.74) PLAUMASP2THPOPRSS1PRSS3
Hydrochloric Acid SCHEMBL30999366 0.84 PRSS1 (0.78) PLAUMASP2THPOPRSS1PRSS3
Hydrochloric Acid SCHEMBL392375 0.84 PRSS1 (0.78) PLAUMASP2THPOPRSS1PRSS3
SCHEMBL251656 0.79 PLAU (0.65) PLAUMASP2THPOPRSS1PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2758 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705448-A1 METHOD FOR THE PRODUCTION OF PHARMACEUTICALLY ACTIVE RECOMBINANT HUMAN LOW MOLECULAR WEIGHT UROKINASE CERBIOS-PHARMA SA (CH) 2026-03-11 EP claimed
US-20250361205-A1 ENZYME-CLEAVABLE METHADONE PRODRUGS AND METHODS OF USE THEREOF ENSYSCE BIOSCIENCES INC (US) 2025-11-27 US claimed
WO-2024227543-A1 METHOD FOR THE PRODUCTION OF PHARMACEUTICALLY ACTIVE RECOMBINANT HUMAN LOW MOLECULAR WEIGHT UROKINASE CERBIOS-PHARMA SA (CH) 2024-11-07 WO claimed
WO-2024059837-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL IN THE BOWL ANIMAL HEALTH, INC. (US) 2024-03-21 WO claimed
US-11918674-B2 Trypsin isoforms and their use ENZYMATICA AB (SE) 2024-03-05 US claimed
EP-4287850-A1 COMPOSITION AND METHOD FOR BIOFORTIFICATION OF FOOD PLANTS AND FOOD PLANTS THUS FORTIFIED FABBRICA COOPERATIVA PERFOSFATI CEREA S.C. (IT) 2023-12-13 EP claimed
CN-113637054-B Purification method and application of recombinant Sendai virus-like particles 雪莱(武汉)生物医药技术有限公司 2023-10-03 CN claimed
CN-113383039-B Moisture curable polyolefin formulation 陶氏环球技术有限责任公司 2023-09-26 CN claimed
CN-115505464-A Compound Chinese prescription cleaning kidney bean and preparation method thereof 青岛锦兰工坊文化传播有限公司 2022-12-23 CN claimed
CN-115385823-A Preparation method of 4-aminobenzamidine dihydrochloride 四川青木制药有限公司 2022-11-25 CN claimed
US-4471053-A ANGIOKINASE EXTRACTED FROM HIGHLY VASCULARIZED MAMMALIAN CONNECTIVE TISSUES; ANTICOAGULANTS; THROMBOSIS SOCIETA ITALO-BRITANNICA L. MANETTI-H. ROBERTS & C. (IT) 1984-09-11 US claimed
EP-0064036-A1 Procedure for producing a vasal fibrinolytic active principle and the enzymatic product so prepared Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) 1982-11-03 EP claimed
US-4252902-A Process for purification of crude kallikrein TOHO PHARMACEUTICAL INDUSTRIES CO., LTD. (JP) 1981-02-24 US claimed
EP-0002723-B1 PHOSPHONYL-UREIDO-BENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION IN DRUGS BAYER AG (DE) 1981-01-21 EP claimed
US-4195128-A LIGAND BOUND TO CARRIER THROUGH PYRIMIDINE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US claimed
EP-0002723-A1 Phosphonyl-ureido-benzene derivatives, process for their preparation and their application in drugs BAYER AG (DE) 1979-07-11 EP claimed
US-4144128-A Polymeric carrier bound ligands BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US claimed
US-4018814-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-19 US claimed
US-4013676-A NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed
US-3996247-A ANTHELMINTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed