Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.94 |
| ▸ | MASP2 | O00187 | 1/20 | 0.94 |
| ▸ | THPO | P40225 | 1/20 | 0.94 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.90 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.90 |
| ▸ | F2 | P00734 | 4/20 | 0.90 |
| ▸ | APEX1 | P27695 | 1/20 | 0.90 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150756 | 0.97 | PLAU (1.00) | PLAUMASP2THPOPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL236095 | 0.94 | PRSS1 (1.00) | PLAUMASP2THPOPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL538862 | 0.94 | PRSS1 (1.00) | PLAUMASP2THPOPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL28256621 | 0.92 | PRSS1 (0.95) | PLAUMASP2THPOPRSS1PRSS3 | |
| Carbamic Acid SCHEMBL28064780 | 0.87 | PLAU (0.81) | PLAUMASP2THPOPRSS1PRSS3 | |
| SCHEMBL537030 | 0.85 | LMNA (0.77) | PLAUMASP2THPOPRSS1PRSS3 | |
| Acetic Acid SCHEMBL7398032 | 0.84 | MASP2 (0.74) | PLAUMASP2THPOPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.82 | PRSS1 (0.78) | PLAUMASP2THPOPRSS1PRSS3 | |
| Hydrochloric Acid SCHEMBL392375 | 0.82 | PRSS1 (0.78) | PLAUMASP2THPOPRSS1PRSS3 | |
| SCHEMBL394218 | 0.77 | WDR5 (0.80) | PLAUMASP2THPOPRSS1PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330568-B | Preparation method for p-aminobenzamidine hydrochloride | 山东省医学科学院药物研究所 | 2017-05-10 | — | — | CN | claimed |
| CN-105330568-A | Preparation method for p-aminobenzamidine hydrochloride | INST OF MATERIA MEDICA SHANDONG ACADEMY OF MEDICAL SCIENCES | 2016-02-17 | — | — | CN | claimed |
| CN-105330568-B | Preparation method for p-aminobenzamidine hydrochloride | 山东省医学科学院药物研究所 | 2017-05-10 | — | — | CN | disclosed |
| CN-105330568-A | Preparation method for p-aminobenzamidine hydrochloride | INST OF MATERIA MEDICA SHANDONG ACADEMY OF MEDICAL SCIENCES | 2016-02-17 | — | — | CN | disclosed |