Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.81 |
| ▸ | MASP2 | O00187 | 1/20 | 0.81 |
| ▸ | THPO | P40225 | 1/20 | 0.81 |
| ▸ | F2 | P00734 | 5/20 | 0.77 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.77 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.77 |
| ▸ | APEX1 | P27695 | 1/20 | 0.77 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.52 |
| ▸ | C1S | P09871 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7398032 | 0.91 | MASP2 (0.74) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL150756 | 0.90 | PLAU (1.00) | PLAUMASP2THPOF2PRSS1 | |
| Hydrochloric Acid SCHEMBL538862 | 0.87 | PRSS1 (1.00) | PLAUMASP2THPOF2PRSS1 | |
| Hydrochloric Acid SCHEMBL236095 | 0.87 | PRSS1 (1.00) | PLAUMASP2THPOF2PRSS1 | |
| Ammonia Solution, Strong SCHEMBL28058272 | 0.87 | PLAU (0.94) | PLAUMASP2THPOF2PRSS1 | |
| Hydrochloric Acid SCHEMBL28256621 | 0.85 | PRSS1 (0.95) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL3876947 | 0.80 | TP53 (0.63) | PLAUMASP2THPOF2PRSS1 | |
| Aminobenzoic Acid SCHEMBL1638859 | 0.80 | TSHR (0.63) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL537030 | 0.79 | LMNA (0.77) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL9342118 | 0.78 | PRSS1 (0.64) | PLAUMASP2THPOF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566296-A | Method for preparing dabigatran amidated impurities | BENGBU BBCA MEDICINE SCIENCE & DEV CO LTD | 2016-05-11 | — | — | CN | disclosed |