SCHEMBL15079779

SCHEMBL15079779

N#Cc1ccc(OCC2(c3ccccc3O)CC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
CYP11B1 P15538 1/20 0.38
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
KCNA5 P22460 1/20 0.36
USP2 O75604 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP2 P08253 1/20 0.36
HRH3 Q9Y5N1 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HRH2 P25021 1/20 0.36
HRH1 P35367 1/20 0.36
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15079366 0.82 KDM4E (0.44) MAPTALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL15079880 0.82 LTA4H (0.43) MAOBTSHRSMN1; SMN2HRH3
SCHEMBL15079895 0.82 ATF4 (0.40) MAPTALDH1A1TSHRMEN1KMT2A
SCHEMBL15079886 0.82 LMNA (0.39) MAPTALDH1A1SMN1; SMN2HRH3HRH1
SCHEMBL15079775 0.79 MAPT (0.39) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL15079426 0.78 CYP26A1 (0.34) MAOBMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL15079849 0.78 SMN1; SMN2 (0.42) MAOBMAPTALDH1A1TSHRSMN1; SMN2
SCHEMBL15079790 0.78 PKM (0.51) CYP3A4TSHR
SCHEMBL15079756 0.78 KMT2A (0.39) MAPTALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL15079856 0.78 MEN1 (0.45) MAOBMAPTKCNA5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 MAOB 484/4885CYP11B1 827/4885MAPT 3297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.