SCHEMBL15079783

SCHEMBL15079783

Oc1ccccc1CCOc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPO P05164 6/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 3/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
JAK2 O60674 1/20 0.48
SLC6A4 P31645 1/20 0.46
TYR P14679 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19825667 0.87 MAPT (0.63) MPOL3MBTL1LMNAGAAMAPT
SCHEMBL897950 0.85 GAA (0.67) MPOLMNAGAAMAPTTAAR1
SCHEMBL9854722 0.81 MPO (0.51) MPOL3MBTL1TDP1LMNAGAA
SCHEMBL15079892 0.79 LMNA (0.53) MPOL3MBTL1TDP1LMNAGAA
SCHEMBL15080025 0.79 L3MBTL1 (0.67) L3MBTL1TDP1MAPTTAAR1ALDH1A1
SCHEMBL15079786 0.79 LMNA (0.48) L3MBTL1TDP1LMNAGAAMAPT
SCHEMBL8702088 0.75 MPO (0.65) MPOTAAR1SLC6A4KDM4E
SCHEMBL301840 0.75 GAA (0.62) MPOLMNAGAAMAPTTAAR1
SCHEMBL9854724 0.74 KCNA3 (0.52) MPOTAAR1TYRNPC1RAB9A
SCHEMBL2089982 0.74 L3MBTL1 (0.58) L3MBTL1TDP1LMNARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2015-01-01 US disclosed
WO-2013093320-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS DIVERCHIM (FR) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004110-A1 NOVEL ANTI-AGING AND DEPIGMENTING COSMETIC COMPOSITIONS ARG1, TYR, NOS1 MPO 66/4885L3MBTL1 719/4885TDP1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.