Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17660546 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| Hydrogen Peroxide SCHEMBL28864226 | 0.80 | CPT2 (0.50) | ALDH1A1TDP1MMP8CYP2C19KDM4E | |
| SCHEMBL1067575 | 0.80 | CPT2 (0.50) | ALDH1A1TDP1MMP8CYP2C19KDM4E | |
| SCHEMBL6055135 | 0.78 | MMP8 (0.36) | ALDH1A1MMP8CYP2C19 | |
| SCHEMBL10216230 | 0.78 | MMP8 (0.32) | MMP8CYP2C19 | |
| SCHEMBL7907381 | 0.78 | KDM4E (0.33) | MMP8CYP2C19KDM4E | |
| SCHEMBL2612030 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP2C19KDM4EFFAR1 | |
| SCHEMBL182348 | 0.76 | MMP8 (0.35) | MMP8 | |
| SCHEMBL7518619 | 0.76 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| SCHEMBL811747 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751271-A | Application of transcription factor OsNAC021 as negative regulation factor in improving content of volatile metabolites of rice | 海南大学三亚南繁研究院 | 2023-09-15 | — | — | CN | disclosed |
| US-20230183222-A1 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2023-06-15 | — | — | US | disclosed |
| US-9809824-B2 | CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170197949-A1 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
| US-20160095938-A1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN, INC. | 2016-04-07 | — | — | US | disclosed |
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | BUSHELL SIMON (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130252883-A1 | Macrocycles and Their Uses | NOVARTIS AG (CH) | 2013-09-26 | — | — | US | disclosed |
| US-8476224-B2 | Macrocycles and their uses | NOVARTIS AG (US) | 2013-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252883-A1 | Macrocycles and Their Uses | MRPL21, CLPP, MLEC | ALDH1A1 3067/4885TDP1 4364/4885MMP8 18/4885 |
| US-20170197949-A1 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, OPRL1 | ALDH1A1 250/4885TDP1 2258/4885MMP8 241/4885 |
| US-20230183222-A1 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, OPRL1 | ALDH1A1 250/4885TDP1 2258/4885MMP8 241/4885 |
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | ABAT, AADAT, GOT2 | ALDH1A1 353/4885TDP1 1091/4885MMP8 452/4885 |
| US-20160095938-A1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | PCNA, EPCAM, MKI67 | ALDH1A1 96/4885TDP1 876/4885MMP8 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.