Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756984 | 0.83 | GAA (0.38) | HIF1AALDH1A1GAAPLOD2TP53 | |
| SCHEMBL153149 | 0.83 | LMNA (0.58) | LMNAHIF1AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL9756896 | 0.76 | CES2 (0.38) | HDAC1NPC1RAB9AKCNK3 | |
| SCHEMBL9756855 | 0.74 | CES2 (0.41) | LMNAHDAC1HDAC6ALDH1A1NPC1 | |
| SCHEMBL13715634 | 0.73 | RAB9A (0.56) | LMNAALDH1A1NPC1TP53RAB9A | |
| SCHEMBL9756986 | 0.73 | RAB9A (0.39) | LMNAALDH1A1GAANPC1TP53 | |
| SCHEMBL9756827 | 0.73 | ALDH1A1 (0.41) | LMNAHDAC1ALDH1A1GAANPC1 | |
| SCHEMBL4185777 | 0.70 | KDM4D (0.51) | HDAC1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL151398 | 0.70 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2NAMPTKCNK3 | |
| SCHEMBL9756903 | 0.70 | RAB9A (0.44) | ALDH1A1GAANPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | claimed |
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |