SCHEMBL1533040

SCHEMBL1533040

OCCCC(F)(F)C(F)(F)Br

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543762 0.97 TSHR (0.30) TSHR
SCHEMBL246920 0.82
SCHEMBL3929610 0.77
SCHEMBL27785024 0.77 SMN1; SMN2 (0.33) TSHRSMN1; SMN2
SCHEMBL338407 0.77 SMN1; SMN2 (0.33) TSHRSMN1; SMN2
SCHEMBL14732305 0.74 SMN1; SMN2 (0.32) TSHRSMN1; SMN2
SCHEMBL864384 0.74 SMN1; SMN2 (0.32) TSHRSMN1; SMN2
SCHEMBL14763324 0.74
SCHEMBL10333533 0.74 SMN1; SMN2 (0.32) TSHRSMN1; SMN2
SCHEMBL12589634 0.72 SMN1; SMN2 (0.36) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11592746-B2 Radiation-sensitive resin composition, resist pattern-forming method, compound and method of generating acid JSR CORPORATION (JP) 2023-02-28 US disclosed
US-20200341376-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIST PATTERN-FORMING METHOD, COMPOUND AND METHOD OF GENERATING ACID JSR CORPORATION (JP) 2020-10-29 US disclosed
CN-104570600-B Coloring composition, colored cured film, and display element JSR株式会社 2020-08-25 CN disclosed
US-20110112306-A1 Novel Sulfonic Acid Salt and Derivative thereof, Photo-Acid Generator, and Process for Production of Sulfonic Acid Salt CENTRAL GLASS COMPANY, LIMITED (JP) 2011-05-12 US disclosed
US-20110112306-A1 Novel Sulfonic Acid Salt and Derivative thereof, Photo-Acid Generator, and Process for Production of Sulfonic Acid Salt CENTRAL GLASS COMPANY, LIMITED (JP) 2011-05-12 US disclosed
US-7897821-B2 Sulfonium compound JSR CORPORATION (JP) 2011-03-01 US disclosed
US-7897821-B2 Sulfonium compound JSR CORPORATION (JP) 2011-03-01 US disclosed
US-20100324329-A1 COMPOUND JSR CORPORATION (JP) 2010-12-23 US disclosed
US-20100324329-A1 COMPOUND JSR CORPORATION (JP) 2010-12-23 US disclosed
US-7812105-B2 Compound, polymer, and radiation-sensitive composition JSR CORPORATION (JP) 2010-10-12 US disclosed
US-7812105-B2 Compound, polymer, and radiation-sensitive composition JSR CORPORATION (JP) 2010-10-12 US disclosed
US-20090069521-A1 Novel Compound, Polymer, and Radiation-Sensitive Composition JSR CORPORATION (JP) 2009-03-12 US disclosed
US-20090069521-A1 Novel Compound, Polymer, and Radiation-Sensitive Composition JSR CORPORATION (JP) 2009-03-12 US disclosed
EP-1897869-A1 NOVEL COMPOUND, POLYMER AND RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324329-A1 COMPOUND AFF2, AFF1, AFF4 TSHR 890/4885SMN1; SMN2 1699/4885
US-20090069521-A1 Novel Compound, Polymer, and Radiation-Sensitive Composition MRE11, RAD51, MRPS22 TSHR 2355/4885SMN1; SMN2 1360/4885
US-20200341376-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIST PATTERN-FORMING METHOD, COMPOUND AND METHOD OF GENERATING ACID RER1, TAS1R1, RAD51 TSHR 247/4885SMN1; SMN2 3147/4885
US-20110112306-A1 Novel Sulfonic Acid Salt and Derivative thereof, Photo-Acid Generator, and Process for Production of Sulfonic Acid Salt ASIC1, FGFR1, PFAS TSHR 1269/4885SMN1; SMN2 2668/4885
US-11592746-B2 Radiation-sensitive resin composition, resist pattern-forming method, compound and method of generating acid RER1, TAS1R1, RAD51 TSHR 247/4885SMN1; SMN2 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.