Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.30 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831679 | 0.77 | CHEK1 (0.31) | — | |
| SCHEMBL6856498 | 0.76 | LMNA (0.40) | — | |
| SCHEMBL30849389 | 0.72 | ENPP2 (0.36) | ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL10382826 | 0.72 | MEN1 (0.35) | — | |
| SCHEMBL7261316 | 0.71 | ELANE (0.35) | — | |
| SCHEMBL476880 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL12485977 | 0.69 | CCNB2 (0.44) | — | |
| SCHEMBL17509871 | 0.69 | — | — | |
| SCHEMBL7429745 | 0.68 | NFE2L2 (0.36) | — | |
| SCHEMBL29956095 | 0.68 | PAX8 (0.40) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459216-B1 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2013-10-30 | — | — | EP | disclosed |
| EP-2459216-A2 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | Novartis AG (CH) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011027222-A2 | IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |