Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27540685 | 0.82 | MCL1 (0.37) | ALDH1A1TSHRCES2CES1DAO | |
| Benzene SCHEMBL28228740 | 0.80 | BBOX1 (0.37) | ALDH1A1TSHRCES2CES1DAO | |
| Acetic Acid SCHEMBL14764595 | 0.78 | CES2 (0.42) | ALDH1A1TSHRCES2CES1DAO | |
| Cyanide SCHEMBL28004471 | 0.78 | CA2 (0.32) | ALDH1A1TSHRALOX15L3MBTL1TDP1 | |
| SCHEMBL29127374 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| Hydrochloric Acid SCHEMBL28762594 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL28801712 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL28234151 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL27838470 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO | |
| Ammonia Solution, Strong SCHEMBL27691225 | 0.77 | BBOX1 (0.35) | ALDH1A1TSHRCES2CES1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289104-A1 | ALIPHATIC AMINO ACID BIOSYNTHESIS INHIBITORS AND A METHOD OF SYNTHESIZING THE SAME | Sardari, Soroush (IR) | 2013-10-31 | — | — | US | disclosed |
| US-8569361-B1 | Aliphatic amino acid biosynthesis inhibitors and a method of synthesizing the same | SARDARI SOROUSH (IR) | 2013-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289104-A1 | ALIPHATIC AMINO ACID BIOSYNTHESIS INHIBITORS AND A METHOD OF SYNTHESIZING THE SAME | DDC, BCAT2, BCAT1 | ALDH1A1 2838/4885TSHR 3516/4885CES2 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.