Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864705 | 0.90 | DRD2 (0.47) | DRD3DRD2MAPTADRB1P2RX7 | |
| SCHEMBL6081885 | 0.87 | MAPT (0.55) | GSK3BMAPTADRB1LMNATP53 | |
| SCHEMBL29652020 | 0.84 | GSK3B (0.50) | GSK3BMAPTLMNATP53MAPK1 | |
| SCHEMBL8938754 | 0.73 | LMNA (0.53) | LMNATP53MAPK1ADRA2CROCK1 | |
| SCHEMBL25026229 | 0.72 | ALDH1A1 (0.55) | ADRB1LMNATP53MAPK1ROCK1 | |
| Hydrochloric Acid SCHEMBL10547839 | 0.72 | MAPK1 (0.51) | MAPTLMNATP53MAPK1ADRA2C | |
| SCHEMBL8934707 | 0.71 | SMN1; SMN2 (0.49) | MAPTADRB1LMNATP53MAPK1 | |
| SCHEMBL5716298 | 0.71 | ALDH1A1 (0.50) | MAPTLMNATP53MAPK1ROCK1 | |
| SCHEMBL5923921 | 0.71 | ALDH1A1 (0.49) | P2RX7LMNATP53MAPK1ROCK1 | |
| SCHEMBL8845412 | 0.71 | SPR (0.41) | GSK3BMAPTLMNATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2656857-A1 | Oral liquid formulation | The Jordanian Pharmaceutical Manufacturing Co. (JO) | 2013-10-30 | — | — | EP | disclosed |