SCHEMBL15401975

SCHEMBL15401975

COC(=O)C(O)c1ccccc1COc1ccccc1C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
KMT2A Q03164 3/20 0.43
FABP4 P15090 2/20 0.43
FABP5 Q01469 2/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 3/20 0.41
NISCH Q9Y2I1 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
LPAR1 Q92633 3/20 0.39
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
ADRB2 P07550 2/20 0.38
ADRB1 P08588 2/20 0.38
ADRB3 P13945 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15402604 0.88 BCHE (0.38) KMT2AFABP4FABP5MEN1LPAR1
SCHEMBL15375381 0.88 MAPT (0.45) LMNAKMT2AFABP4FABP5MEN1
SCHEMBL15401433 0.87 LPAR1 (0.45) LMNAKMT2AFABP4FABP5MEN1
SCHEMBL15402142 0.86 FABP4 (0.43) FABP4FABP5
SCHEMBL15375470 0.86 RXRA (0.45) FABP4FABP5ALDH1A1L3MBTL1CYP1A2
SCHEMBL15375371 0.86 FABP4 (0.57) LMNAKMT2AFABP4FABP5MEN1
SCHEMBL15401423 0.85 LMNA (0.43) LMNAKMT2AFABP4FABP5MEN1
SCHEMBL15375554 0.85 FABP4 (0.44) LMNAKMT2AFABP4FABP5MEN1
SCHEMBL15401943 0.83 RXRA (0.48) FABP4FABP5ALDH1A1NISCH
SCHEMBL15375596 0.82 LTA4H (0.46) LMNAKMT2AFABP4FABP5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA LMNA 4708/4885KMT2A 777/4885FABP4 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.