Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 5/20 | 0.53 |
| ▸ | CDK2 | P24941 | 4/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CDC7 | O00311 | 6/20 | 0.49 |
| ▸ | PIM1 | P11309 | 5/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.49 |
| ▸ | PRKACA | P17612 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.49 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.49 |
| ▸ | CLK2 | P49760 | 3/20 | 0.49 |
| ▸ | CDK7 | P50613 | 3/20 | 0.49 |
| ▸ | PRKX | P51817 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26174486 | 0.86 | TGFBR1 (0.53) | DYRK1ACLK1CDK9CDK2CCNT1 | |
| SCHEMBL16720088 | 0.83 | DYRK1A (0.44) | DYRK1ACLK1CDK9CDK2CCNT1 | |
| SCHEMBL101422 | 0.81 | CDK9 (0.54) | DYRK1ACLK1CDK9CDK2CCNT1 | |
| SCHEMBL29720400 | 0.75 | ALDH1A1 (0.51) | CDK9CDK2CCNT1CCNA2CKS1B | |
| SCHEMBL28809049 | 0.75 | ALDH1A1 (0.51) | CDK9CDK2CCNT1CCNA2CKS1B | |
| SCHEMBL5618155 | 0.75 | TGFBR1 (0.71) | DYRK1ACDK9CDK2CCNT1CCNA2 | |
| SCHEMBL26174487 | 0.74 | RIPK1 (0.57) | DYRK1ACDK9CDK2CCNT1CCNA2 | |
| SCHEMBL858166 | 0.74 | MAP3K5 (0.54) | DYRK1ACDK9CDK2CCNT1CCNA2 | |
| SCHEMBL15436394 | 0.73 | CDC7 (0.50) | DYRK1ACDK9CDK2CCNT1CCNA2 | |
| SCHEMBL18357388 | 0.73 | CYP19A1 (0.50) | DYRK1ACLK1CDK9CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |