SCHEMBL1546684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11002167	0.83	KIF11 (0.54)	ALDH1A1CA1CA2CA9KIF11
	SCHEMBL15881512	0.81	ALDH1A1 (0.48)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	Hydrochloric Acid SCHEMBL28031229	0.79	ALDH1A1 (0.47)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	SCHEMBL10987264	0.78	HTR6 (0.54)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	SCHEMBL27909560	0.76	ALDH1A1 (0.48)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	SCHEMBL2371802	0.76	OXTR (0.47)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	SCHEMBL10988990	0.76	GAA (0.59)	ALDH1A1KDM4ETDP1CA1CA2
	SCHEMBL2371804	0.76	SMN1; SMN2 (0.52)	ALDH1A1KDM4ETDP1PTPRZ1PTPN1
	SCHEMBL11574176	0.75	TSHR (0.56)	ALDH1A1TDP1CA1CA2CA9
	SCHEMBL10978202	0.72	HSD11B1 (0.57)	ALDH1A1KDM4ETDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.