SCHEMBL15468630

SCHEMBL15468630

BrC1=CC(c2cccc(-c3ccccc3)c2)CC=C1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.33
HTR2C P28335 4/20 0.33
HTR2B P41595 4/20 0.33
HRH3 Q9Y5N1 2/20 0.33
MAOA P21397 2/20 0.33
SLC5A2 P31639 1/20 0.33
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24863100 0.89 CRHBP (0.34) ALDH1A1MAPK1CRHBPCRHR2
SCHEMBL24672038 0.85 KDM1A (0.38) KDM1AALDH1A1MAPK1
SCHEMBL19027577 0.82 KDM1A (0.43) HTR2AHTR2CHTR2BKDM1AALDH1A1
SCHEMBL18960615 0.80 GABRG2 (0.38) MAOAKDM1AALDH1A1
SCHEMBL19593309 0.74 HTR2A (0.31) HTR2AHTR2CHTR2BHRH3
SCHEMBL19061473 0.72 ADORA3 (0.35) ALDH1A1MAPK1
SCHEMBL24689878 0.72 L3MBTL1 (0.33) ALDH1A1
SCHEMBL22428531 0.70 HTR1A (0.35) HRH3ALDH1A1
SCHEMBL27948099 0.68 NPC1 (0.48) HTR2AHTR2CHTR2BHRH3MAOA
SCHEMBL22665208 0.67 MAOA (0.44) MAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2695882-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL, COMPOSITION CONTAINING SAID COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Mitsubishi Chemical Corporation (JP) 2014-02-12 EP disclosed