Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054259 | 0.91 | CA12 (0.41) | CNR1CNR2CA12CA1CA2 | |
| SCHEMBL15520544 | 0.89 | MCL1 (0.35) | CNR1CNR2ACLYNOD1LMNA | |
| SCHEMBL15520543 | 0.89 | RXRA (0.39) | CNR1CNR2ACLYPTGER4TRPM8 | |
| SCHEMBL2365154 | 0.83 | RXRA (0.39) | CNR1CNR2ACLYPTGER4NOD1 | |
| SCHEMBL12096852 | 0.82 | ACLY (0.53) | CNR1ACLY | |
| SCHEMBL15519817 | 0.78 | TRPM8 (0.37) | PTGER4TRPM8LMNARXRARXRB | |
| SCHEMBL14054088 | 0.77 | NOD1 (0.40) | NOD1 | |
| SCHEMBL15520182 | 0.75 | PPARG (0.35) | NOD1 | |
| SCHEMBL14124725 | 0.75 | NOD1 (0.40) | NOD1 | |
| SCHEMBL14053826 | 0.74 | MRGPRX4 (0.35) | CNR1CNR2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | disclosed |