SCHEMBL177674

SCHEMBL177674

Clc1cc(Cl)cc(OBOc2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
IDO1 P14902 2/20 0.33
SOD1 P00441 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.32
AHR P35869 1/20 0.31
TPMT P51580 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15521815 0.83 ALDH1A1 (0.50) CYP3A4IDO1CYP2C19ALDH1A1AHR
SCHEMBL16783445 0.83 HCAR1 (0.39) TSHRCYP3A4ALDH1A1
SCHEMBL3541751 0.83 RAPGEF4 (0.32) TSHRMAPTCYP3A4ALDH1A1
SCHEMBL874186 0.83 EPAS1 (0.38)
SCHEMBL14664933 0.78 TSHR (0.42) TSHRMAPTTP53CYP3A4IDO1
SCHEMBL4617695 0.78 KCNH2 (0.41) CYP3A4
SCHEMBL240715 0.74 WDR5 (0.44) TSHRCYP2C19ALDH1A1
SCHEMBL875081 0.72 CHRNB2 (0.46) MAPT
SCHEMBL10706723 0.71 TSHR (0.57) TSHRMAPTTP53CYP3A4IDO1
SCHEMBL98774 0.71 LMNA (0.47) MAPTCYP3A4IDO1CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3149138-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE The Procter & Gamble Company (US) 2017-04-05 EP claimed
WO-2015184209-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2015-12-03 WO claimed
US-20150344817-A1 WATER CLUSTER-DOMINANT BORONIC ACID ALKALI SURFACTANT COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY 2015-12-03 US claimed
WO-2004009752-A1 ALKALINE LIQUID DETERGENT COMPOSITION CJ CORPORATION (KR) 2004-01-29 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
US-20250359479-A1 Light Emitting Device SAMSUNG DISPLAY CO., LTD. (KR) 2025-11-20 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
US-12448391-B2 Bicyclic derivatives for treating endoparasites ELANCO TIERGESUNDHEIT AG (CH) 2025-10-21 US disclosed
US-20250129094-A1 NEW QUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-24 US disclosed
EP-4514777-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2025-03-05 EP disclosed
EP-3897842-B1 BICYCLIC DERIVATIVES ELANCO TIERGESUNDHEIT AG (CH) 2025-01-29 EP disclosed
EP-0544488-B1 Substituted phenyl phenol leukotriene antagonists LILLY CO ELI (US) 1998-03-11 EP disclosed
EP-0802968-A1 STABILIZATION OF LIQUID ENZYME COMPOSITIONS NOVO NORDISK A/S (DK) 1997-10-29 EP disclosed
WO-1996036347-A1 USE OF LEUKOTRIENE ANTAGONISTS FOR ALZHEIMER'S DISEASE ELI LILLY AND COMPANY (US) 1996-11-21 WO disclosed
EP-0743064-A1 Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease ELI LILLY AND COMPANY (US) 1996-11-20 EP disclosed
WO-1996021716-A1 STABILIZATION OF LIQUID ENZYME COMPOSITIONS NOVO NORDISK A/S (DK) 1996-07-18 WO disclosed
US-5462954-A Antiinflammatory, antiallergens; treating asthma ELI LILLY AND COMPANY (US) 1995-10-31 US disclosed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO disclosed
EP-0544488-A2 Substituted phenyl phenol leukotriene antagonists ELI LILLY AND COMPANY (US) 1993-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B TSHR 2806/4885MAPT 3253/4885TP53 4664/4885
US-12448391-B2 Bicyclic derivatives for treating endoparasites TBXA2R, PIGS, CYCS TSHR 3891/4885MAPT 4735/4885TP53 4879/4885
US-20250359479-A1 Light Emitting Device CRY1, LAGE3, CRY2 TSHR 3414/4885MAPT 1799/4885TP53 4752/4885
US-20250129094-A1 NEW QUINOLINE DERIVATIVES RECQL, QTRT2, NQO2 TSHR 2519/4885MAPT 3341/4885TP53 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.