Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.69 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.69 |
| ▸ | HTR3B | O95264 | 5/20 | 0.69 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.69 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.69 |
| ▸ | HTR5A | P47898 | 1/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | KHK | P50053 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15534114 | 0.98 | HTR3A (0.67) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL3138664 | 0.81 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL25618223 | 0.81 | TERT (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL30870394 | 0.81 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL6645952 | 0.81 | ADRB1 (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL81940 | 0.81 | ADRB1 (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL29688470 | 0.80 | HTR3A (0.96) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL15708159 | 0.80 | HTR3A (0.96) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL6637697 | 0.79 | HTR1A (0.94) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL20859429 | 0.79 | HTR3E (0.59) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177253-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |