Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590433 | 0.73 | FABP6 (0.41) | MAOBCYP19A1KDM4EHSD17B10PKM | |
| SCHEMBL6590831 | 0.73 | MAOB (0.46) | MAOB | |
| SCHEMBL10623756 | 0.73 | CASP1 (0.38) | KDM4EHSD17B10TSHRNPC1RAB9A | |
| SCHEMBL4728144 | 0.73 | MAOA (0.42) | MAOBKDM4EPKMTSHRMAOA | |
| SCHEMBL6590210 | 0.72 | ACHE (0.34) | KDM4E | |
| 3-Coumaranone SCHEMBL69412 | 0.71 | PKM (0.56) | MAOBADORA3ARCYP19A1KDM4E | |
| 3-Coumaranone SCHEMBL29420742 | 0.71 | PKM (0.56) | MAOBADORA3ARCYP19A1KDM4E | |
| SCHEMBL9854612 | 0.70 | CYP19A1 (0.50) | MAOBCYP19A1KDM4ECYP3A4 | |
| SCHEMBL7218336 | 0.69 | ALDH1A1 (0.46) | KDM4EHSD17B10CES1BCHENPC1 | |
| SCHEMBL6645873 | 0.68 | MAOA (0.47) | MAOBCYP19A1KDM4EPKMMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 854 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487899-B1 | POLYTRIMETHYLENE TEREPHTHALATE RESINS WITH IMPROVED PROPERTIES | ZIMMER AG (DE) | 2006-01-04 | — | — | EP | claimed |
| EP-0454060-B1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | DROESSLER KARL PROF DR (DE) | 1996-07-03 | — | — | EP | claimed |
| EP-0454060-A1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-10-30 | — | — | EP | claimed |
| US-6423486-B1 | — | — | None | — | — | US | disclosed |
| US-10752782-B2 | Radiation curable compositions | AGFA NV (BE) | 2020-08-25 | — | — | US | disclosed |
| US-20200047466-A1 | LAMINATED SAFETY GLASS | AGFA GRAPHICS NV (BE) | 2020-02-13 | — | — | US | disclosed |
| US-10549508-B2 | Laminated safety glass | AGFA NV (BE) | 2020-02-04 | — | — | US | disclosed |
| US-20170355858-A1 | RADIATION CURABLE COMPOSITIONS | AGFA NV (BE) | 2017-12-14 | — | — | US | disclosed |
| EP-3233477-A1 | RADIATION CURABLE COMPOSITIONS | Agfa Graphics NV (BE) | 2017-10-25 | — | — | EP | disclosed |
| EP-2486040-B1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LTD (GB) | 2017-06-21 | — | — | EP | disclosed |
| US-20160303831-A1 | LAMINATED SAFETY GLASS | AGFA NV (BE) | 2016-10-20 | — | — | US | disclosed |
| US-4923792-A | BENZYLIDENE LEUCO COMPOUNDS AS COLOR-GENERATING REDUCING AGENTS, TOPCOAT OF POLYVINYL ALCOHOL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0343206-A1 | PROCESS FOR THE SYNTHESIS OF 3-THIO-4-QUINOLONE DERIVATIVES AND INTERMEDIATE COMPOUNDS FOR USE THEREIN, AND THEIR USE AS MEDICAMENTS | The Boots Company PLC (GB) | 1989-11-29 | — | — | EP | disclosed |
| US-4883747-A | LIGHT SENSITIVE SILVER HALIDE, ORGANIC ACID SILVER SALT, LEUCO DYE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| WO-1989004827-A1 | PROCESS FOR THE SYNTHESIS OF 3-THIO-4-QUINOLONE DERIVATIVES AND INTERMEDIATE COMPOUNDS FOR USE THEREIN, AND THEIR USE AS MEDICAMENTS | THE BOOTS COMPANY PLC (GB) | 1989-06-01 | — | — | WO | disclosed |
| EP-0317149-A1 | Process for the synthesis of 3-thio-4-quinolone derivatives and intermediate compounds for use therein, and their use as medicaments | The Boots Company PLC (GB) | 1989-05-24 | — | — | EP | disclosed |
| US-4728673-A | BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-01 | — | — | US | disclosed |
| US-4369316-A | 3,1 Benzoxazine 2,4-dione | ICI AMERICAS INC. (US) | 1983-01-18 | — | — | US | disclosed |
| US-4302460-A | 4-Quinolinones having antihypertensive activity | THE BOOTS COMPANY LIMITED (GB) | 1981-11-24 | — | — | US | disclosed |
| US-3725321-A | BLOWING AGENTS | BAYER AG (DE) | 1973-04-03 | — | — | US | disclosed |