Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540022 | 0.89 | POLB (0.48) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL15539199 | 0.87 | SGMS2 (0.50) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL16714093 | 0.80 | MAOA (0.41) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL15540208 | 0.80 | MAPT (0.46) | POLBABCB1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL15538819 | 0.76 | LMNA (0.38) | POLBABCB1LMNACYP1A2CYP2D6 | |
| SCHEMBL15539763 | 0.76 | ABCB1 (0.48) | POLBABCB1TSHRNPSR1 | |
| SCHEMBL1913817 | 0.74 | KDM4E (0.53) | LMNACYP1A2SMN1; SMN2TSHRMEN1 | |
| SCHEMBL16730223 | 0.74 | HTR1A (0.52) | POLBABCB1LMNASMN1; SMN2TP53 | |
| SCHEMBL15539841 | 0.74 | HTR1A (0.52) | POLBABCB1LMNASMN1; SMN2TP53 | |
| SCHEMBL15539857 | 0.72 | ABCB1 (0.52) | POLBABCB1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | claimed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | claimed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | claimed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | claimed |
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | disclosed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | POLB 3154/4885ABCB1 1296/4885LMNA 2899/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | POLB 3154/4885ABCB1 1296/4885LMNA 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.