Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543250 | 0.81 | SIGMAR1 (0.46) | MAPTLMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL15542803 | 0.81 | TSHR (0.64) | MAPTLMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL15542801 | 0.81 | TSHR (0.64) | MAPTLMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL15543166 | 0.80 | FKBP1A (0.51) | MAPTLMNAHTTSMN1; SMN2RECQL | |
| SCHEMBL15543282 | 0.79 | MDH1 (0.45) | MAPTLMNAHTTTSHRENPP2 | |
| SCHEMBL15543672 | 0.76 | KEAP1 (0.44) | LMNASMN1; SMN2ENPP2ALDH1A1GAA | |
| SCHEMBL4729104 | 0.75 | PPARD (0.52) | SMN1; SMN2 | |
| SCHEMBL15543206 | 0.74 | L3MBTL1 (0.51) | HTTSMN1; SMN2ENPP2KDM4E | |
| SCHEMBL15543066 | 0.74 | TSHR (0.61) | MAPTLMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL15543065 | 0.74 | TSHR (0.61) | MAPTLMNAHTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864309-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | Cadila Healthcare Limited (IN) | 2015-04-29 | — | — | EP | disclosed |
| WO-2014002105-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |