⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670252 | 0.88 | LMNA (0.38) | — | |
| SCHEMBL15825855 | 0.78 | FABP4 (0.32) | — | |
| SCHEMBL16669029 | 0.77 | — | — | |
| SCHEMBL9619844 | 0.71 | CYP1A2 (0.44) | — | |
| SCHEMBL15825702 | 0.69 | FABP4 (0.37) | — | |
| SCHEMBL15825905 | 0.68 | L3MBTL1 (0.38) | — | |
| SCHEMBL15826663 | 0.67 | BTK (0.31) | — | |
| SCHEMBL16668811 | 0.67 | CYP1A2 (0.34) | — | |
| SCHEMBL16668882 | 0.66 | CYP1A2 (0.35) | — | |
| Methylamine SCHEMBL27967387 | 0.64 | L3MBTL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688608-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688608-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688608-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2017-06-27 | — | — | US | disclosed |
| US-20160039741-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9204646-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9204646-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9204646-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2015-12-08 | — | — | US | disclosed |
| EP-2877456-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2015-06-03 | — | — | EP | disclosed |
| US-20150119242-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20150119242-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20150119242-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | US | disclosed |
| WO-2013167548-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-11-14 | — | — | WO | disclosed |