Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15837492 | 0.85 | BTK (0.31) | BTK | |
| SCHEMBL15825905 | 0.78 | L3MBTL1 (0.38) | BTK | |
| SCHEMBL15825855 | 0.69 | FABP4 (0.32) | — | |
| SCHEMBL15545132 | 0.67 | — | — | |
| SCHEMBL15825702 | 0.64 | FABP4 (0.37) | — | |
| SCHEMBL16670252 | 0.62 | LMNA (0.38) | — | |
| SCHEMBL15832378 | 0.61 | — | — | |
| SCHEMBL15826550 | 0.60 | L3MBTL1 (0.42) | — | |
| SCHEMBL11960180 | 0.57 | BCL2L1 (0.50) | CES1 | |
| SCHEMBL11960176 | 0.55 | DRD2 (0.48) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935218-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095677-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-26 | — | — | WO | disclosed |