Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545132 | 0.88 | — | — | |
| SCHEMBL16668811 | 0.79 | CYP1A2 (0.34) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16668882 | 0.77 | CYP1A2 (0.35) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15825702 | 0.77 | FABP4 (0.37) | L3MBTL1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL15825905 | 0.76 | L3MBTL1 (0.38) | LMNANPY5RL3MBTL1KDM4ESMN1; SMN2 | |
| Methylamine SCHEMBL27967387 | 0.74 | L3MBTL1 (0.45) | LMNANPY5RL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL1085493 | 0.74 | CYP1A2 (0.48) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10341113 | 0.72 | CYP1A2 (0.38) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15532491 | 0.72 | L3MBTL1 (0.33) | LMNANPY5RL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8613128 | 0.71 | SMN1; SMN2 (0.46) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688608-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2017-06-27 | — | — | US | disclosed |
| US-20160039741-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9204646-B2 | Pyrazole tetrahydronaphthyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20150119242-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039741-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | TPMT, HDHD5, CBR3 | LMNA 3773/4885CYP1A2 267/4885CYP2C9 334/4885 |
| US-20150119242-A1 | PYRAZOLE TETRAHYDRONAPHTHYL CARBOXAMIDES | TPMT, HDHD5, CBR3 | LMNA 3773/4885CYP1A2 267/4885CYP2C9 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.