Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825855 | 0.88 | FABP4 (0.32) | FABP4FABP5 | |
| SCHEMBL28901441 | 0.80 | RAB9A (0.36) | L3MBTL1RAB9ASMN1; SMN2RECQLNPC1 | |
| SCHEMBL15825905 | 0.78 | L3MBTL1 (0.38) | FABP4FABP5L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL16670252 | 0.77 | LMNA (0.38) | L3MBTL1SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL12903702 | 0.75 | HTT (0.51) | L3MBTL1RAB9ASMN1; SMN2RECQLNPC1 | |
| SCHEMBL2911307 | 0.74 | RAB9A (0.46) | L3MBTL1RAB9ASMN1; SMN2RECQLNPC1 | |
| SCHEMBL13478940 | 0.72 | ALDH1A1 (0.43) | L3MBTL1RAB9ASMN1; SMN2RECQLNPC1 | |
| SCHEMBL28901449 | 0.72 | BACE1 (0.34) | RAB9ASMN1; SMN2RECQLNPC1TP53 | |
| SCHEMBL13064249 | 0.71 | TSHR (0.50) | RAB9ARECQLNPC1KDM4EALDH1A1 | |
| SCHEMBL15826550 | 0.71 | L3MBTL1 (0.42) | FABP4FABP5L3MBTL1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630943-B2 | Tetrahydronaphthyl(thio) carboxamides | BAYER CROPSCIENCE AG (DE) | 2017-04-25 | — | — | US | disclosed |
| US-20150329517-A1 | TETRAHYDRONAPHTHYL(THIO) CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-11-19 | — | — | US | disclosed |
| EP-2935223-A1 | TETRAHYDRONAPHTHYL(THIO) CARBOXAMIDES | Bayer CropScience AG (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095678-A1 | TETRAHYDRONAPHTHYL(THIO) CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329517-A1 | TETRAHYDRONAPHTHYL(THIO) CARBOXAMIDES | HDHD5, TPMT, TIAL1 | FABP4 3684/4885FABP5 2517/4885L3MBTL1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.