Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15826550 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15826663 | 0.78 | BTK (0.31) | BTK | |
| SCHEMBL15825702 | 0.78 | FABP4 (0.37) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16670252 | 0.76 | LMNA (0.38) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15825760 | 0.75 | PTGES (0.34) | MAPTIRAK4KDRPOLB | |
| SCHEMBL20440050 | 0.71 | KDM4E (0.41) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30173408 | 0.71 | KDM4E (0.41) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15825855 | 0.70 | FABP4 (0.32) | FABP4FABP5 | |
| SCHEMBL24403564 | 0.70 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15545132 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428459-B2 | Difluoromethyl-nicotinic- tetrahydronaphtyl carboxamides | BAYER CROPSCIENCE AG (DE) | 2016-08-30 | — | — | US | disclosed |
| US-20150322013-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | BAYER CROPSCIENCE AG (US) | 2015-11-12 | — | — | US | disclosed |
| EP-2935218-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095677-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322013-A1 | DIFLUOROMETHYL-NICOTINIC- TETRAHYDRONAPHTYL CARBOXAMIDES | NAPRT, NNMT, NAMPT | L3MBTL1 3982/4885MEN1 1377/4885KMT2A 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.