Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HINT1 | P49773 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.30 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15629327 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1P2RX3P2RX2ADORA3 | |
| SCHEMBL15629245 | 0.78 | PRMT6 (0.43) | ADORA3SLC29A1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL15629326 | 0.77 | THRB (0.34) | NT5E | |
| SCHEMBL24258545 | 0.75 | TAS1R3 (0.51) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL15629382 | 0.68 | BCHE (0.47) | TAS1R3TAS1R1ADORA3BCHESLC29A1 | |
| SCHEMBL15629246 | 0.68 | TYMP (0.38) | ADORA3BCHENT5ESLC29A1 | |
| SCHEMBL15626256 | 0.68 | TAS1R3 (0.47) | TAS1R3TAS1R1P2RX3P2RX2HINT1 | |
| SCHEMBL11654898 | 0.67 | BCHE (0.57) | ADORA3BCHE | |
| SCHEMBL11451041 | 0.67 | BCHE (0.57) | ADORA3BCHE | |
| SCHEMBL15629254 | 0.66 | HINT1 (0.43) | HINT1NT5EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | NT5C2, NT5E, ENPP3 | TAS1R3 3734/4885TAS1R1 4075/4885P2RX3 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.