SCHEMBL15712969

SCHEMBL15712969

Cc1cc2c(c(-c3ccccc3)c1C)C=C(Br)C2

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.31
AKT1 P31749 1/20 0.30
AKT2 P31751 1/20 0.30
AKT3 Q9Y243 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18393653 0.94 ACHE (0.31)
SCHEMBL2235659 0.81 AKT2 (0.31) MAPTKDM4EKMT2AAKT1AKT2
SCHEMBL2236464 0.78 ALDH1A1 (0.34) ALDH1A1AKT1AKT2AKT3
SCHEMBL15712971 0.74 PTGS1 (0.40) MAPTKDM4EMEN1ALDH1A1PKM
SCHEMBL2234205 0.73 ALDH1A1 (0.34) RAB9AALDH1A1NPC1
SCHEMBL17060048 0.71 MAPT (0.34) MAPTRAB9AKDM4EMEN1ALDH1A1
SCHEMBL18393559 0.70 PTGS1 (0.37) MAPTKDM4EMEN1ALDH1A1PKM
SCHEMBL18393491 0.70 MEN1 (0.30) MEN1KMT2A
SCHEMBL18406630 0.70
SCHEMBL4191158 0.70 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483670-B Metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2021-11-30 CN disclosed
EP-3121187-B1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER JAPAN POLYPROPYLENE CORP (JP) 2018-10-10 EP disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9963522-B2 Metallocene complex and method for producing olefin polymer JAPAN POLYPROPYLENE CORPORATION (JP) 2018-05-08 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
US-9902749-B2 Metallocene complex and olefin polymerization method JAPAN POLYPROPYLENE CORPORATION (JP) 2018-02-27 US disclosed
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2017-03-23 US disclosed
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2017-03-23 US disclosed
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2017-03-23 US disclosed
EP-3121187-A1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2017-01-25 EP disclosed
CN-106132975-A metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2016-11-16 CN disclosed
EP-2915816-B1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORP (JP) 2016-05-25 EP disclosed
WO-2015141675-A1 METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER 日本ポリプロ株式会社 2015-09-24 WO disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD JAPAN POLYPROPYLENE CORPORATION (JP) 2015-09-24 US disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 EP disclosed
EP-2915816-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD Japan Polypropylene Corporation (JP) 2015-09-09 EP disclosed
CN-104781270-A Metallocene complexes and olefin polymerization process JAPAN POLYPROPYLENE CORP 2015-07-15 CN disclosed
WO-2014069391-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD 日本ポリプロ株式会社 (JP) 2014-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170081431-A1 METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER PPOX, ALOX12, PORCN MAPT 1613/4885RAB9A 4782/4885KDM4E 4257/4885
US-20150266914-A1 METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD POR, OPRM1, ALOX12 MAPT 2002/4885RAB9A 4741/4885KDM4E 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.