Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745596 | 0.95 | MAPT (0.49) | POLBHTTMAPTACKR3CYP1A2 | |
| SCHEMBL22277150 | 0.85 | ACKR3 (0.45) | ACKR3CYP1A2ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL21801340 | 0.83 | POLB (0.44) | POLBHTTMAPTCYP1A2CHRNB2 | |
| SCHEMBL18134700 | 0.83 | POLB (0.44) | POLBHTTMAPTCYP1A2CHRNB2 | |
| SCHEMBL19544407 | 0.81 | CYP1A2 (0.46) | ACKR3CYP1A2ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL19544406 | 0.79 | CYP1A2 (0.47) | ACKR3CYP1A2ALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL16328043 | 0.79 | CYP1A2 (0.47) | ACKR3CYP1A2ALDH1A1CHRNB2CHRNA5 | |
| SCHEMBL19708766 | 0.79 | CYP1A2 (0.47) | CYP1A2ALDH1A1CHRM3CHRNB2CHRNA5 | |
| SCHEMBL18502526 | 0.78 | MAPT (0.43) | POLBHTTMAPTCYP1A2CHRNB2 | |
| SCHEMBL18502527 | 0.78 | MAPT (0.43) | POLBHTTMAPTCYP1A2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381200-B2 | Nitrogen containing compounds | WOCKHARDT LIMITED (IN) | 2016-07-05 | — | — | US | disclosed |
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2015-11-19 | — | — | US | disclosed |
| US-8987297-B2 | Nitrogen containing compounds | WOCKHARDT LTD. (IN) | 2015-03-24 | — | — | US | disclosed |
| US-20150005285-A1 | Nitrogen containing compounds | WOCKHARDT LIMITED (IN) | 2015-01-01 | — | — | US | disclosed |
| US-8853197-B1 | Nitrogen containing compounds | WOCKHARDT LTD. (IN) | 2014-10-07 | — | — | US | disclosed |
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-09-18 | — | — | US | disclosed |
| US-8822450-B2 | 1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | WOCKHARDT LTD. (IN) | 2014-09-02 | — | — | US | disclosed |
| US-20140148431-A1 | 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | WOCKHARDT LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005285-A1 | Nitrogen containing compounds | NOS2, NOS1, NCF1 | POLB 1174/4885HTT 4646/4885MAPT 4078/4885 |
| US-20140148431-A1 | 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | ODC1, AOC1, CASP7 | POLB 500/4885HTT 4804/4885MAPT 4760/4885 |
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | POLB 1174/4885HTT 4646/4885MAPT 4078/4885 |
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | POLB 1174/4885HTT 4646/4885MAPT 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.