Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745587 | 0.95 | POLB (0.49) | MAPTCYP1A2POLBHTTACKR3 | |
| SCHEMBL18502527 | 0.83 | MAPT (0.43) | MAPTCYP1A2POLBHTT | |
| SCHEMBL18502526 | 0.83 | MAPT (0.43) | MAPTCYP1A2POLBHTT | |
| SCHEMBL22277150 | 0.80 | ACKR3 (0.45) | CYP1A2ACKR3ALDH1A1TERT | |
| SCHEMBL18688759 | 0.80 | CYP1A2 (0.55) | CYP1A2ADRA2ADRD1HRH2HTR2A | |
| SCHEMBL21801340 | 0.78 | POLB (0.44) | MAPTCYP1A2POLBHTT | |
| SCHEMBL18134700 | 0.78 | POLB (0.44) | MAPTCYP1A2POLBHTT | |
| SCHEMBL19544407 | 0.76 | CYP1A2 (0.46) | CYP1A2ACKR3ALDH1A1 | |
| SCHEMBL26896069 | 0.75 | CYP1A2 (0.50) | CYP1A2ADRA2ADRD1HRH2HTR2A | |
| SCHEMBL13584823 | 0.75 | POLB (0.49) | MAPTPOLBHTTCTSDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381200-B2 | Nitrogen containing compounds | WOCKHARDT LIMITED (IN) | 2016-07-05 | — | — | US | disclosed |
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2015-11-19 | — | — | US | disclosed |
| US-9132133-B2 | Nitrogen containing compounds | WOCKHARDT LTD. (IN) | 2015-09-15 | — | — | US | disclosed |
| US-20150174133-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2015-06-25 | — | — | US | disclosed |
| US-8987297-B2 | Nitrogen containing compounds | WOCKHARDT LTD. (IN) | 2015-03-24 | — | — | US | disclosed |
| US-20150005285-A1 | Nitrogen containing compounds | WOCKHARDT LIMITED (IN) | 2015-01-01 | — | — | US | disclosed |
| US-8853197-B1 | Nitrogen containing compounds | WOCKHARDT LTD. (IN) | 2014-10-07 | — | — | US | disclosed |
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-09-18 | — | — | US | disclosed |
| US-8822450-B2 | 1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | WOCKHARDT LTD. (IN) | 2014-09-02 | — | — | US | disclosed |
| US-20140148431-A1 | 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | WOCKHARDT LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174133-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | MAPT 4078/4885CYP1A2 870/4885POLB 1174/4885 |
| US-20150005285-A1 | Nitrogen containing compounds | NOS2, NOS1, NCF1 | MAPT 4078/4885CYP1A2 870/4885POLB 1174/4885 |
| US-20140148431-A1 | 1,6- Diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections | ODC1, AOC1, CASP7 | MAPT 4760/4885CYP1A2 208/4885POLB 500/4885 |
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | MAPT 4078/4885CYP1A2 870/4885POLB 1174/4885 |
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | MAPT 4078/4885CYP1A2 870/4885POLB 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.