Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.57 |
| ▸ | PPARA | Q07869 | 5/20 | 0.57 |
| ▸ | F7 | P08709 | 5/20 | 0.57 |
| ▸ | F3 | P13726 | 5/20 | 0.57 |
| ▸ | TERT | O14746 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | FABP4 | P15090 | 3/20 | 0.57 |
| ▸ | TOP1 | P11387 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL157682 | 1.00 | PPARG (0.57) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL22042310 | 1.00 | PPARG (0.57) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL10939346 | 0.92 | PPARG (0.49) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL5197277 | 0.92 | PPARG (0.49) | PPARGPPARDPPARAF7F3 | |
| Palmitic Acid SCHEMBL10937075 | 0.92 | GPR84 (0.50) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Dodecanoate SCHEMBL6028403 | 0.92 | GPR84 (0.50) | PPARGPPARDPPARAPTPN1HSD17B10 | |
| Linoleic Acid SCHEMBL10937223 | 0.89 | PPARG (0.52) | PPARGPPARDPPARAF7F3 | |
| Linolenic Acid SCHEMBL16915309 | 0.83 | ALDH1A1 (0.52) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL17511721 | 0.81 | PRKCA (0.43) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL6341349 | 0.80 | PPARG (0.70) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| US-20120321576-A1 | SUNSCREEN COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | claimed |
| CN-115135307-B | Cell delivery vehicle | 株式会社ITO | 2024-11-22 | — | — | CN | disclosed |
| EP-3714863-B1 | COSMETIC | SAKAI CHEMICAL INDUSTRY CO (JP) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024135446-A1 | SOLID HAIR TREATMENT | 資生堂ホネケーキ工業株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-11964043-B2 | Method of emulsification using core-corona type microparticles | SHISEIDO COMPANY, LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| WO-2024075548-A1 | GEL COMPOSITION AND OIL-IN-WATER-TYPE COMPOSITION | 株式会社 資生堂 | 2024-04-11 | — | — | WO | disclosed |
| WO-2024071313-A1 | COSMETIC COMPOSITION AND COSMETIC | 株式会社日本触媒 | 2024-04-04 | — | — | WO | disclosed |
| WO-2024059862-A2 | FIBROIN PEPTIDES AND PROTEIN FRAGMENTS COMPOSITIONS | EVOLVED BY NATURE, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-11883514-B2 | Stable low pH personal care compositions and methods for the same | COLGATE-PALMOLIVE COMPANY (US) | 2024-01-30 | — | — | US | disclosed |
| EP-3520772-B1 | COSMETIC RAW MATERIAL USING CORE-CORONA TYPE MICROPARTICLES AND OIL-IN-WATER TYPE EMULSION COSMETIC | SHISEIDO CO LTD (JP) | 2023-12-20 | — | — | EP | disclosed |
| EP-1550429-A1 | EXTERNAL PREPARATIONS FOR SKIN | SHISEIDO COMPANY, LTD. (JP) | 2005-07-06 | — | — | EP | disclosed |
| US-20040197361-A1 | External preparation for the skin | SHISEIDO COMPANY, LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
| EP-1430905-A1 | EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO COMPANY LIMITED (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-6607736-B2 | Endermic liniment comprising diethoxy ethyl succinate and humectant | SHISEIDO COMPANY, LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030091603-A1 | Skin preparations for external use | SHISEIDO COMPANY, LTD. (JP) | 2003-05-15 | — | — | US | disclosed |
| US-20030003071-A1 | Hair growth stimulant | SHISEIDO COMPANY, LTD. (JP) | 2003-01-02 | — | — | US | disclosed |
| EP-1234574-A1 | HAIR GROWTH STIMULANT | SHISEIDO COMPANY LIMITED (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-1153602-A1 | SKIN PREPARATIONS FOR EXTERNAL USE | SHISEIDO COMPANY LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-4552754-A | Hair cosmetic composition | LION CORPORATION (JP) | 1985-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091603-A1 | Skin preparations for external use | CUTA, POLR1C, ACMSD | PPARG 3833/4885PPARD 3921/4885PPARA 3481/4885 |
| US-11964043-B2 | Method of emulsification using core-corona type microparticles | LIPA, CORO1A, CLTA | PPARG 2709/4885PPARD 3477/4885PPARA 446/4885 |
| US-20040197361-A1 | External preparation for the skin | CUTA, DDOST, DSG1 | PPARG 533/4885PPARD 1651/4885PPARA 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.