Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775364 | 0.84 | ALDH1A1 (0.49) | EIF4EMAPTALDH1A1POLBTDP1 | |
| SCHEMBL15775580 | 0.83 | ALDH1A1 (0.46) | EIF4EMAPTLMNAALDH1A1POLB | |
| SCHEMBL15775543 | 0.81 | LMNA (0.45) | EIF4EACP1MAPTNPSR1LMNA | |
| SCHEMBL15775490 | 0.80 | ACP1 (0.46) | ACP1LMNAF2RL3TDP1HSD11B1 | |
| Ammonia Solution, Strong SCHEMBL2444716 | 0.80 | EIF4E (0.41) | EIF4EACP1MAPTNPSR1LMNA | |
| SCHEMBL15775417 | 0.80 | LMNA (0.45) | EIF4EMAPTNPSR1LMNAPOLB | |
| SCHEMBL2442608 | 0.77 | CRHR1 (0.43) | EIF4EACP1MAPTNPSR1LMNA | |
| SCHEMBL15776164 | 0.77 | SQOR (0.47) | EIF4EACP1MAPTNPSR1LMNA | |
| SCHEMBL15775322 | 0.75 | TDP1 (0.41) | MAPTLMNAALDH1A1POLBTDP1 | |
| SCHEMBL15775590 | 0.74 | NPC1 (0.49) | EIF4EMAPTLMNAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |