Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.38 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775105 | 0.82 | SQOR (0.53) | PTPN1CYP1A2CYP2C19CYP2D6SQOR | |
| SCHEMBL15775484 | 0.81 | L3MBTL1 (0.48) | CYP1A2CYP2C19SQORTRPM8CYP3A4 | |
| SCHEMBL15775449 | 0.81 | L3MBTL1 (0.48) | CYP1A2CYP2C19SQORTRPM8CYP3A4 | |
| SCHEMBL15775175 | 0.80 | EIF4E (0.43) | ACP1F2RL3HSD11B1CTSKTDP1 | |
| SCHEMBL15775248 | 0.79 | PARP1 (0.47) | ACP1SQORKDM4ETDP1ACHE | |
| SCHEMBL15775546 | 0.78 | XDH (0.47) | F2RL3SQORCTSKTSHRKDM4E | |
| SCHEMBL15775748 | 0.75 | SQOR (0.53) | ACP1SQORKDM4EHSD17B10 | |
| SCHEMBL2442608 | 0.75 | CRHR1 (0.43) | ACP1PTPN1F2RL3CYP1A2CYP2C19 | |
| SCHEMBL6220344 | 0.73 | ACP1 (0.40) | ACP1PTPN1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL15775195 | 0.72 | HSP90AA1 (0.47) | PTPN1CYP1A2CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |