Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167021 | 0.89 | SMN1; SMN2 (0.57) | RAB9AKDM4EKCNK3KCNK9ALDH1A1 | |
| SCHEMBL7574902 | 0.89 | TP53 (0.55) | RAB9AKDM4EKCNK9ALDH1A1HPGD | |
| SCHEMBL7028467 | 0.89 | KCNK3 (0.59) | RAB9AKDM4EKCNK3KCNK9ALDH1A1 | |
| SCHEMBL15775343 | 0.88 | LMNA (0.58) | KDM4EKCNK3KCNK9ALDH1A1LMNA | |
| SCHEMBL15775483 | 0.88 | ALDH1A1 (0.54) | RAB9AKDM4EKCNK3KCNK9ALDH1A1 | |
| SCHEMBL15775203 | 0.86 | TAS1R3 (0.47) | RAB9AKCNK3KCNK9LMNAKMT2A | |
| SCHEMBL7570311 | 0.84 | KMT2A (0.54) | RAB9AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL15775319 | 0.83 | KDM4E (0.59) | RAB9AKDM4EKCNK3KCNK9ALDH1A1 | |
| SCHEMBL7018503 | 0.80 | MAPK1 (0.51) | RAB9AKDM4EKCNK3KCNK9ALDH1A1 | |
| SCHEMBL28066437 | 0.79 | CTSD (0.45) | RAB9AKDM4EKCNK3KCNK9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |