Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 11/20 | 0.49 |
| ▸ | ACP1 | P24666 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775442 | 0.89 | SQOR (0.48) | SQORACP1ALDH1A1MEN1KMT2A | |
| SCHEMBL15775748 | 0.84 | SQOR (0.53) | SQORACP1KDM4EALDH1A1 | |
| SCHEMBL15775389 | 0.83 | ESR1 (0.45) | SQORKDM4EALDH1A1NPC1MAPT | |
| SCHEMBL13443755 | 0.81 | SQOR (0.57) | SQORACP1KDM4EALDH1A1NPC1 | |
| SCHEMBL15775312 | 0.80 | SQOR (0.44) | SQORACP1KDM4EALDH1A1NPC1 | |
| SCHEMBL15775248 | 0.80 | PARP1 (0.47) | SQORACP1KDM4ENPC1MAPT | |
| SCHEMBL15775799 | 0.77 | SQOR (0.54) | SQORKDM4EALDH1A1GAAMAPT | |
| SCHEMBL15775605 | 0.76 | NR1I3 (0.53) | SQOR | |
| SCHEMBL15775546 | 0.73 | XDH (0.47) | SQORKDM4EALDH1A1GAA | |
| SCHEMBL15775195 | 0.73 | HSP90AA1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |