Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775605 | 0.85 | NR1I3 (0.53) | SQORNR1I3MAP4K4TLR8 | |
| SCHEMBL15775748 | 0.82 | SQOR (0.53) | SQORKDM4EALDH1A1HPGDSYK | |
| SCHEMBL15775546 | 0.82 | XDH (0.47) | SQORKDM4EALDH1A1HPGDGAA | |
| SCHEMBL15775442 | 0.82 | SQOR (0.48) | SQORCYP1A2CYP3A4CYP2C9ADORA2A | |
| SCHEMBL15775389 | 0.81 | ESR1 (0.45) | SQORCYP1A2CYP3A4CYP2C9ADORA2A | |
| SCHEMBL21586163 | 0.80 | MAP4K4 (0.56) | SQORCYP1A2CYP3A4VDRCYP2C9 | |
| SCHEMBL15775590 | 0.78 | NPC1 (0.49) | SQORCYP1A2CYP3A4VDRCYP2C9 | |
| SCHEMBL15775248 | 0.77 | PARP1 (0.47) | SQORKDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL15775763 | 0.77 | SQOR (0.49) | SQORADORA2AKDM4EALDH1A1KMT2A | |
| SCHEMBL15775195 | 0.76 | HSP90AA1 (0.47) | CYP1A2NR1I3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |