Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 7/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775763 | 0.89 | SQOR (0.49) | SQORADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL15775799 | 0.82 | SQOR (0.54) | SQORADORA2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL15775605 | 0.81 | NR1I3 (0.53) | SQOR | |
| SCHEMBL15775231 | 0.80 | SQOR (0.43) | SQORXDHCTSSCTSKMEN1 | |
| SCHEMBL15775748 | 0.78 | SQOR (0.53) | SQORALDH1A1ACP1IDO1 | |
| SCHEMBL15775546 | 0.78 | XDH (0.47) | SQORXDHCTSSCTSKALDH1A1 | |
| SCHEMBL15775389 | 0.76 | ESR1 (0.45) | SQORADORA2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL15775248 | 0.73 | PARP1 (0.47) | SQORACP1IDO1 | |
| SCHEMBL15775195 | 0.72 | HSP90AA1 (0.47) | CYP1A2CYP2C19CLK4ALDH1A1 | |
| SCHEMBL7019095 | 0.72 | ADORA1 (0.60) | SQORADORA2AMEN1KMT2ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |