Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.53 |
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775799 | 0.85 | SQOR (0.54) | NR1I3SQORMAP4K4TLR8 | |
| SCHEMBL15775195 | 0.81 | HSP90AA1 (0.47) | NR1I3 | |
| SCHEMBL15775748 | 0.81 | SQOR (0.53) | SQOR | |
| SCHEMBL15775442 | 0.81 | SQOR (0.48) | SQOR | |
| SCHEMBL15775546 | 0.81 | XDH (0.47) | SQORF2RL3TLR8 | |
| SCHEMBL15775389 | 0.80 | ESR1 (0.45) | SQORTACR3 | |
| SCHEMBL15775156 | 0.79 | NR1I3 (0.48) | NR1I3SQORF2RL3TACR3PDGFRB | |
| SCHEMBL15775484 | 0.78 | L3MBTL1 (0.48) | NR1I3SQORTACR3 | |
| SCHEMBL15775449 | 0.78 | L3MBTL1 (0.48) | NR1I3SQORTACR3 | |
| SCHEMBL15775763 | 0.76 | SQOR (0.49) | SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |